Skip to main content

Table 4 Multivariate analysis of predictors for mortality and cancer-specific death after PSM

From: The efficacy of surgery in advanced hepatocellular carcinoma: a cohort study

CharacteristicsMultivariate analysis
Overall survival, HR (95% CI)P valueCancer-specific survival, HR (95% CI)P value
Gender    
 MaleReference Reference 
 Female1.121 (0.890, 1.411)0.3320.912 (0.696, 1.194)0.501
Age at diagnosis    
 30–44Reference Reference 
 45–592.384 (1.369, 4.153)0.0022.874 (1.539, 5.365)0.001
 60–742.397 (1.382, 4.158)0.0023.055 (1.645, 5.674)< 0.001
 75–842.631 (1.456, 4.757)0.0013.059 (1.562, 5.993)0.001
Ethnicity    
 WhiteReference Reference 
 Black0.913 (0.706, 1.181)0.4900.844 (0.634, 1.121)0.844
 Others0.8886 (0.675, 1.162)0.3800.959 (0.709, 1.296)0.959
Marital status    
 MarriedReference Reference 
 Single0.968 (0.800, 1.172)0.7411.026 (0.832, 1.264)0.812
 Others1.323 (0.792, 2.209)0.2851.429 (0.837, 2.442)0.191
AJCC T stage    
 T1Reference Reference 
 T21.324 (1.044, 1.679)0.0211.381 (1.054, 1.811)0.019
 T31.316 (1.024, 1.691)0.0321.359 (1.031, 1.790)0.030
 T41.766 (1.028, 3.034)0.0391.682 (0.941, 3.008)0.079
 TX1.462 (0.588, 3.633)0.4131.322 (0.478, 3.661)0.591
Year of diagnosis    
 2004–2006Reference Reference 
 2007–20090.903 (0.711, 1.147)0.2190.852 (0.655, 1.108)0.232
 2010–20121.027 (0.798, 1.322)0.8340.932 (0.701, 1.239)0.627
 2013–20150.976 (0.748, 1.274)0.8580.886 (0.659, 1.192)0.423
Tumor size    
 ≤ 3 cmReference Reference 
 3–5 cm1.355 (1.040, 1.767)0.0251.556 (1.149, 2.107)0.004
 > 5 cm1.940 (1.462, 2.575)< 0.0012.173 (1.557, 3.032)< 0.001
Tumor number    
 1Reference Reference 
 20.746 (0.538, 1.035)0.4990.927 (0.450, 1.906)0.927
 30.307 (0.125, 0.754)0.010N0.923
 > 31.546 (0.483, 4.954)0.463NN
Radiotherapy    
 YesReference Reference 
 No1.765 (1.194, 2.607)0.0041.931 (1.262, 2.953)0.002
Chemotherapy    
 YesReference Reference 
 No1.660 (1.383, 1.991)< 0.0011.852 (1.510, 2.271)< 0.001
Surgery    
 YesReference Reference 
 No2.150 (1.750, 2.641)< 0.0012.213 (1.760, 2.781)< 0.001