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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Inhibition of HIF1A-AS1 promoted starvation-induced hepatocellular carcinoma cell apoptosis by reducing HIF-1α/mTOR-mediated autophagy

Fig. 2

HIF1A-AS1 expression was increased in HCC cells exposed to starvation. a The relative expression of HIF1A-AS1 was detected in HCC cell lines (7721 and Huh7) and normal hepatocyte cell line (L02) by qRT-PCR. The HIF1A-AS1 expression in L02 cell line was set as reference, and the relative expression of HIF1A-AS1 in 7721 and Huh7 HCC cell lines was calculated compared with that in L02 cell line. **P < 0.01 vs. L02 group. b The expression changes of HIF1A-AS1 in 7721, Huh7, and L02 cell lines under normal and EBSS culture conditions. **P < 0.01 vs. normal group. c, d The expression changes of HIF1A-AS1 in 7721 and Huh7 HCC cell lines at different starvation time. **P < 0.01 vs. 0 h group

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