Table 4 Prognostic factors associated with disease-free survival in patients with endometrial carcinoma with cervical affection (N = 239)

Age

1.03

1.01–1.05

0.012

Age > 45 years

2.91

1.24–6.81

0.014

5.50

0.94–32.00

0.060

BMI

1.02

0.97–1.06

0.578

Obesity (BMI > 30)

1.29

0.78–2.18

0.350

BPH

2.47

1.45–4.19

0.001

0.89

0.24–3.31

0.867

Tumor size, mm

0.99

0.98–0.99

0.047

0.98

0.96–0.99

0.031

Tumor size > 4 cm

0.72

0.34–1.53

0.395

Grade 1–2 vs. 3–BPH

3.01

1.73–5.23

< 0.001

2.92

0.62–13.64

0.171

LVI

2.62

1.51–4.52

0.001

0.38

0.98–1.53

0.98

Myometrial involvement > 50%

2.33

1.20–4.52

0.012

2.64

0.52–13.33

0.239

Depth of invasion

0.97

0.92–1.02

0.238

Depth invasion/thickness rate

0.77

0.24–2.49

0.658

Ovarian involvement

2.67

1.53–4.67

0.001

0.61

0.14–2.61

0.503

Parametrial involvement

2.91

1.24–6.83

0.014

13.20

0.78–222.04

0.073

Uterine serosa involvement

2.05

0.92–4.54

0.077

0.13

0.001–1.44

0.096

Pelvic node involvement

1.66

0.88–3.12

0.112

2.23

0.56–8.84

0.253

Para-aortic node involvement

1.73

0.88–3.39

0.110

1.67

0.47–5.93

0.426

Distant disease

4.90

2.61–9.21

< 0.001

1.22

0.28–5.32

0.783

Radical hysterectomy

1.23

0.64–2.38

0.535

Radiotherapy

0.29

0.16–0.54

< 0.001

0.116

0.02–0.59

0.001

Chemotherapy

3.36

1.77–6.37

< 0.001

7.86

1.21–51.24

0.031