Skip to main content

Table 3 Prognostic factors associated with overall survival in patients with endometrial carcinoma with cervical involvement (N = 239)

From: What is the impact of radical hysterectomy on endometrial cancer with cervical involvement?

 

Univariate

Multivariate

 

HR

95% CI

p

HR

95% CI

p

Age

1.01

0.98–1.04

0.461

   

 Age > 45 years

1.57

0.69–3.55

0.284

   

BMI

1.01

0.95–1.06

0.717

   

 Obesity (BMI > 30)

1.21

0.64–2.28

0.560

   

BPH

2.34

1.254.43

< 0.001

0.94

0.38–2.26

0.887

Tumor size, mm

0.99

0.98–1.001

0.587

   

 Tumor size > 4 cm

1.01

0.38–2.83

0.991

   

Grade 1-2 vs. 3-BPH

4.49

2.199.22

< 0.001

3.39

1.169.92

0.026

LVI

2.18

1.154.12

0.017

0.52

0.21–1.27

0.152

Myometrial involvement >50%

2.54

1.125.79

0.026

0.97

0.35–2.68

0.958

Depth of invasion

1.01

0.97–1.05

0.660

   

Depth invasion/thickness rate

0.70

0.15–3.18

0.646

   

Ovarian involvement

1.69

0.83–3.47

0.148

   

Parametrial involvement

1.61

0.49–5.22

0.432

   

Uterine serosa involvement

1.43

0.51–4.02

0.495

   

Pelvic node involvement

2.03

0.964.29

0.064

1.16

0.48–2.78

0.740

Para-aortic node involvement

1.87

0.82–4.28

0.136

   

Distant disease

2.38

1.045.45

0.039

0.98

0.31–3.18

0.986

Radical hysterectomy

0.73

0.29–1.87

0.515

   

Radiotherapy

0.32

0.160.63

0.001

0.12

0.040.39

< 0.001

Chemotherapy

2.06

1.044.07

0.037

3.74

1.1612.09

0.027

  1. HR hazard ratio, 95% CI 95% confidence interval, BMI body mass index, BPH bad prognostic histology (serous papillary, clear cell, mixed, carcinosarcoma), LVI lymphovascular invasion