Fig. 1
From: Endoglin (CD105) and VEGF as potential angiogenic and dissemination markers for colorectal cancer
Endoglin and VEGF mRNA expression levels increase in tumor samples comparing with non-tumoral ones. Samples from tumoral and non-tumoral regions from different patients were collected during surgery. RNA was extracted and processed for RT-qPCR of human Endoglin and VEGF genes in colon cancer samples (a) and rectum cancer samples (b). Fold change of mRNA expression levels with respect to levels from non-tumoral samples are indicated. Results were normalized to 18SrRNA as a housekeeping gene, and respect to non-tumoral sample, reason why this value is the same for both genes. *p < 0.05; **p < 0.01; ***p < 0.001 with respect to non-tumoral gene expression. NT, non-tumoral; T, tumoral; Eng, Endoglin; VEGF, Vascular Endothelial Growth Factor