Table 2 Multivariate Cox proportional hazard model for overall survival and disease-free survival of advanced HPSCC patients
From: Treatment patterns and survival outcomes of advanced hypopharyngeal squamous cell carcinoma
Variable | OS | DFS | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Sex | ||||
Female | Reference | Reference | ||
Male | 1.74 (0.82–3.68) | 0.150 | 1.39 (0.72–2.70) | 0.332 |
Age (years) | ||||
< 65 | Reference | Reference | ||
≥ 65 | 1.01 (0.76–1.36) | 0.929 | 0.97 (0.73–1.28) | 0.965 |
Overall stages | ||||
III | Reference | Reference | ||
IVA | 1.67 (1.18–2.35) | 0.004 | 1.64 (1.19–2.26) | 0.057 |
IVB | 2 98 (2.05–4.33) | < 0.001 | 3.01 (2.12–4.27) | < 0.001 |
Histology grade | ||||
WD/MD | Reference | Reference | ||
PD/UD | 0.99 (0.73–1.34) | 0.944 | 0.97 (0.72–1.30) | 0.826 |
Unclassified | 1.06 (0.83–1.35) | 0.632 | 1.10 (0.87–1.38) | 0.440 |
Treatment | ||||
CCRT | Reference | Reference | ||
Surgery | 0.73 (0.57–0.94) | 0.014 | 0.83 (0.66–1.04) | 0.105 |