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Table 2 Subgroup analysis: impact of breast density, age, cancer type and microcalcifications regarding therapy modification after CEM regarding therapy modification

From: Added value of contrast-enhanced mammography (CEM) in staging of malignant breast lesions—a feasibility study

Grouping

Subgroup

Therapy modified after CEM

p value2

Yes, n (%)

No, n (%)

All patients

 

10 (21)

37 (79)

 

Breast density group1

A or B

8 (26)

23 (74)

 

C or D

2 (12)

14 (88)

0.457

Age group3

Below 56

4 (27)

11 (73)

 

56 and above

6 (19)

26 (81)

0.704

Cancer type (index)

Invasive ductal cancer

5 (19)

21 (81)

 

Invasive lobular cancer

2 (25)

6 (75)

 

Other invasive cancer

0

3 (100)

 

DCIS

1 (13)

7 (88)

1.0000

Microcalcifications

No

5 (17)

24 (83)

 

Yes

4 (25)

12 (75)

0.6998

  1. CEM contrast-enhanced mammography, DCIS ductal carcinoma in situ
  2. 1Breast density graded according to BI-RADS®, ACR 5th Edition; A–B, low density; C–D, high density
  3. 2Fisher’s exact test for association between grouping variable and therapy modification
  4. 3Age of 56 defines an expected cut-off between pre- and postmenopausality