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Table 5 Distributions of mean numbers of TDLNs, PDLNs, and NDLNs and the mean positive rates in 42 N(+) CRC patients based on the number of TDLNs

From: A reappraisal of lymph node dissection in colorectal cancer during primary surgical resection

Sub-groups

No. of accumulative cases

No. of TDLNs (mean)

No. of PDLNs (mean )

Positive rate (Mean, %)

No. of NDLNs (Mean)

Overall

42

    

TDLNs ≥ 4

42

21.2

6.2

31.5

15.0

TDLNs ≥ 6

41

21.6

6.3

31.0

15.4

TDLNs ≥ 7

40

22.0

6.4

31.4

15.6

TDLNs ≥ 9

38

22.8

6.7

32.3

16.1

TDLNs ≥ 10

34

24.4

6.9

29.5

17.6

TDLNs ≥ 13

31

25.8

7.2

29.1

18.6

TDLNs ≥ 14

30

26.3

7.4

29.9

18.8

TDLNs ≥ 16

28

27.1

7.4

27.7

19.8

TDLNs ≥ 17

26

28.0

7.7

28.6

20.3

TDLNs ≥ 18

24

28.9

7.8

27.8

21.1

TDLNs ≥ 19

23

29.4

8.1

28.5

21.3

TDLNs ≥ 20

20

31.0

8.6

28.8

22.4

TDLNs ≥ 21*

19

31.5

8.9

29.8

22.6

TDLNs ≥ 23

17

32.8

8.9

28.3

23.9

TDLNs ≥ 24

15

34.1

8.3

24.5

25.7

TDLNs ≥ 25

14

34.8

8.2

23.3

26.6

TDLNs ≥ 27

12

36.4

8.4

22.5

28.0

TDLNs ≥ 28

10

38.3

9.4

24.4

28.9

TDLNs ≥ 29

9

39.4

8.7

20.8

30.8

TDLNs ≥ 30

8

40.8

9.5

22.5

31.3

TDLNs ≥ 34

7

42.3

10.7

25.3

31.6

TDLNs ≥ 35

6

43.7

12.3

29.0

31.3

TDLNs ≥ 36

5

45.4

12.2

27.3

33.2

TDLNs ≥ 41

4

47.8

10.5

21.0

37.3

TDLNs ≥ 47

3

50.0

13.0

25.5

37.0

TDLNs ≥ 51

2

51.5

17.0

33.0

34.5

TDLNs ≥ 52

1

52.0

22.0

42.3

30.0

  1. TDLNs total dissected lymph nodes, PDLNs positive dissected lymph nodes, NDLNs negative dissected lymph nodes, Positive rate No. PDLNs/No. TDLNs, %, SD standard deviation, CI confidence interval, ROC receiver operating characteristic, AUC area under the curve
  2. *We tested various cutoff points for TDLNs on ROC curves (AUC = 0.723, 95%CI = 0.560–0.886, p = 0.022) and 20.5 (i.e., 21, after rounding up 20.5) had the highest Youden index of 0.459 (sensitivity = 0.769, specificity = 0.690) to distinguish PDLNs ≤ 7 or PDLNs > 7