Table 1 The main demographic, clinical, and surgical features of patients with and without anastomotic leakage are presented
| Â | All patients 1432 | Leakage 106 | No leakage 1326 | p value |
|---|---|---|---|---|
Male sex,n(%) | 822 (57.4) | 65 (56.6) | 757 (57.1) | ns |
Age (mean ± SD), years | 65.8 ± 13.7 | 67.4 ± 11.4 | 65.7 ± 13.9 | ns |
BMI (mean ± SD) | 25.1 ± 4.2 | 23.5 ± 4.2 | 25.2 ± 4.1 | 0.0002 |
ASA score (mean ± SD) | 2.2 ± 0.8 | 2.2 ± 0.8 | 2.2 ± 0.8 | ns |
Charlson comorbidity index (mean ± SD) | 5.5 ± 2.3 | 6.5 ± 3.0 | 5.4 ± 2.3 | 0.0017 |
Disease localization | ||||
Right colon,n(%) | 451 (31.5) | 23 (21.7) | 428 (32.3) | ns |
Transverse colon,n(%) | 99 (6.9) | 7 (6.6) | 92 (6.9) | ns |
Left colon,n(%) | 149 (10.4) | 15 (14.1) | 134 (10.1) | ns |
Sigmoid,n(%) | 331 (23.1) | 19 (17.9) | 312 (23.5) | ns |
Rectum,n(%) | 395 (27.6) | 40 (37.7) | 355 (26.8) | ns |
Multiple,n(%) | 7 (0.5) | 2 (1.9) | 5 (0.4) | ns |
AJCC stage | ||||
0,n(%) | 13 (0.9) | 2 (1.9) | 11 (0.8) | ns |
I,n(%) | 242 (16.9) | 16 (15.1) | 226 (17) | ns |
II,n(%) | 470 (32.8) | 21 (19.8) | 449 (33.9) | 0.0353 |
III,n(%) | 526 (36.7) | 55 (51.9) | 471 (35.5) | 0.0368 |
IV,n(%) | 167 (11.7) | 12 (11.3) | 155 (11.7) | ns |
NA,n(%) | 14 (1) | 0 (0) | 14 (1.1) | ns |
Tumor grALing | ||||
G1,n(%) | 193 (13.5) | 9 (8.5) | 184 (13.9) | ns |
G2,n(%) | 1018 (71.1) | 68 (64.1) | 950 (71.6) | ns |
G3,n(%) | 211 (14.7) | 29 (27.4) | 182 (13.7) | 0.0027 |
NA,n(%) | 10 (0.7) | 0 (0) | 10 (0.7) | ns |
Distance from AV, rectal tumors (mean ± SD), cm | 9.5 ± 3.3 | 9.2 ± 3.3 | 9.5 ± 3.3 | ns |
Resection type (total procedures) | 1438 | 106 | 1332 | Â |
Right hemicolectomy,n(%) | 474 (33) | 21 (19.8) | 453 (34) | 0.0337 |
Left hemicolectomy,n(%) | 151 (10.5) | 18 (17) | 133 (10) | ns |
Anterior resection,n(%) | 566 (39.4) | 56 (52.8) | 510 (38.3) | ns |
Trasverse resection,n(%) | 197 (13.7) | 7 (6.6) | 190 (14.3) | ns |
Total colectomy,n(%) | 25 (1.7) | 4 (3.8) | 21 (1.6) | ns |
Other,n(%) | 25 (1.7) | 0 (0) | 25 (1.9) | ns |
Surgical approach | ||||
Open,n(%) | 1060 (74) | 70 (66) | 990 (74.7) | ns |
Laparoscopic,n(%) | 372 (26) | 36 (34) | 336 (25.3) | ns |
Leakage postoperative day, median (95% CI) | – | 6 (5–7) | – | – |
Leakage treatment | ||||
Open,n(%) | – | 77 (72.6) | – | – |
Conservative,n(%) | – | 25 (23.6) | – | – |
NA,n(%) | – | 4 (3.8) | – | – |
Other complications,n(%) | 1152 (80.4) | 53 (50) | 227 (17.1) | 0.0042 |
Length of stay, (mean ± SD), days | 11.7 ± 7.5 | 24.1 ± 17.3 | 10.6 ± 4.4 | < 0,0001 |
30-day mortality | 18 (1.3) | 11(10.4) | 7 (0.5) | < 0,0001 |