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Fig. 4 | World Journal of Surgical Oncology

Fig. 4

From: Selenium nanoparticles (SeNPs) have potent antitumor activity against prostate cancer cells through the upregulation of miR-16

Fig. 4

Microarray analyses reveal a role of SeNPs in microRNA expressions. a The Venn diagrams depict the number of genes regulated by SeNP treatment in LnCaP and LnCaP-A cells identified by microarray analysis. Overlapped regions represent the number of genes regulated by SeNP treatment in both LnCaP and LnCaP-A cells. b Heatmap clustering analysis of microRNA expression profile of the overlapped targets in a in both LnCaP and LnCaP-A cells. Each column represents the microRNAs expression profile. c Fold change of top differentially expressed genes by SeNP treatment. d, e Confirmation of miR-16 expression in d LNCaP and e LNCaP-A after SeNP treatment by qRT-PCR analysis

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World Journal of Surgical Oncology

ISSN: 1477-7819

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