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Table 2 Meta-analysis results of all available studies in measured outcomes

From: Comparison of effect between nasobiliary drainage and biliary stenting in malignant biliary obstruction: a systematic review and updated meta-analysis

Measured outcomes

Subgroup

No. studies

No. patients

Heterogeneity test

Model

RR/WMD

95% CI

P

Begg’s test

 

Egger’s test

    

I2(%)

P

    

Pr > |z|*

Pr > |z|**

P > |t|*

Preoperative cholangitis

Total

9

813 vs. 622

19.1

0.273

Random

0.46

0.34, 0.62

< 0.001

0.404

0.466

0.73

 

HCC

2

145 vs. 53

81.5

0.02

Random

0.5

0.19, 1.3

0.156

--

--

--

 

DBO

4

535 vs. 439

17.4

0.259

Random

0.38

0.26, 0.57

< 0.001

0.174

0.308

0.282

Preoperative pancreatitis

Total

7

750 vs. 508

0

0.929

Fixed

0.69

0.50, 0.95

0.023

0.881

1

0.551

 

HCC

2

145 vs. 53

0

0.999

Fixed

0.67

0.30, 1.47

0.314

--

--

--

 

DBO

3

485 vs. 367

0

0.825

Fixed

0.74

0.50, 1.12

0.152

0.602

1

0.603

Stent dysfunction rate

Total

6

464 vs. 437

38.6

0.149

Random

0.58

0.43, 0.8

0.001

0.188

0.26

0.311

 

HCC

2

145 vs. 53

0

0.319

Random

0.48

0.35, 0.67

< 0.001

--

--

--

 

DBO

2

204 vs. 291

26.3

0.244

Random

0.59

0.39, 0.90

0.015

--

--

--

Morbidity

Total

5

231 vs. 188

0

0.418

Fixed

0.77

0.64, 0.93

0.007

0.142

0.221

0.163

POPF

Total

3

170 vs. 160

7.7

0.338

Fixed

0.65

0.45, 0.92

0.016

0.602

1

0.536

  1. HCC hilar cholangiocarcinoma; DBO distant biliary obstruction; POPF postoperative pancreatic fistula; No.number of; RR risk ratio; WMD weighted mean difference; CI confidence interval
  2. *P value
  3. **P value (continuity corrected)
  4. --Not applicable