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Fig. 3 | World Journal of Surgical Oncology

Fig. 3

From: MiR-489 inhibited the development of gastric cancer via regulating HDAC7 and PI3K/AKT pathway

Fig. 3

HDAC7 was the target of miR-489. a The schematic of the putative targeting sites in the HDAC 3′UTR with miR-489. b Luciferase activity of HDAC7 3′UTR-WT or -MuT in GC cells treated with miR-489 mimic, miR-489 inhibitor, and control. c HDAC7 protein level. d HDAC7 mRNA level in GC cells treated with miR-489 mimic miR-489 inhibitor, and control. Western blots have been performed three times. e miR-489 was inversely associated with HDAC7 expression. (r = − 0.8642, P < 0.001). *P < 0.05, **P < 0.01

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