| General information | Preoperative IM therapy | Operation | ||||||
---|---|---|---|---|---|---|---|---|---|
No. | G/A (years) | Tumor location | Mutation analysis | P/R | Dose (mg/day) | Duration (months) | Assessed before IM therapy | Performing after IM therapy | Margin status |
1 | F/50 | Stomach | KIT E11 mut. | P | 400 | 4 | Total gastrectomy | Partial gastrectomy combined with spleen resection | R0 |
2 | M/50 | Stomach | KIT E11 mut. | P | 400 | 6 | Total gastrectomy | Partial gastrectomy (laparoscopic) | R0 |
3 | M/48 | Stomach | KIT E11 mut. | P | 400 | 6 | Total gastrectomy | Partial gastrectomy (laparoscopic) | R0 |
4 | M/63 | Stomach | KIT E11 mut. | P | 400 | 3 | Total gastrectomy | Partial gastrectomy | R0 |
5 | F/65 | Stomach | KIT E11 mut. | P | 400 | 7 | Total gastrectomy | Partial gastrectomy (laparoscopic) | R0 |
6 | M/59 | Stomach | Wild-type | P | 400 | 4 | Proximal gastrectomy | Proximal gastrectomy | R0 |
7 | F/68 | Stomach | KIT E11 and E13 mut. | P | 400 | 7 | Total gastrectomy | Partial gastrectomy | R0 |
8 | M/58 | Stomach and liver | KIT E11 mut. | R | 400 | 8 | Unresectable | Partial gastrectomy combined with spleen resection | R2 |
9 | M/70 | Stomach | KIT E11 mut. | P | 400 | 12 | Total gastrectomy | Partial gastrectomy | R0 |
10 | M/58 | Stomach | KIT E11 mut. | R | 400 | 26 | Unresectable | Partial gastrectomy | R0 |
11 | F/44 | Stomach | KIT E11 mut. | P | 400 | 11 | Total gastrectomy | Partial gastrectomy | R0 |
12 | F/31 | Stomach | KIT E11 mut. | R | 400 | 8 | Unresectable | Partial gastrectomy | R0 |
13 | F/22 | Stomach | KIT E11 mut. | P | 400 | 10 | Total gastrectomy | Partial gastrectomy | R0 |
14 | F/40 | Stomach | KIT E11 mut. | P | 400 | 9 | Total gastrectomy | Partial gastrectomy | R0 |
15 | M/46 | Small intestine | Wild-type | P | 400 | 9 | Pancreaticoduodenectomy | Pancreaticoduodenectomy | R0 |
16 | F/53 | Small intestine | KIT E9 mut. | P | 600 | 4 | Pancreaticoduodenectomy | Partial duodenum resection | R0 |
17 | M/38 | Small intestine | KIT E11 mut. | P | 400 | 7 | Pancreaticoduodenectomy | Pancreaticoduodenectomy | R0 |
18 | M/67 | Small intestine | KIT E9 mut. | R | 600 | 10 | Unresectable | Local resection of liver | R0 |
19 | M/47 | Small intestine | KIT E9 mut. | R | 600 | 8 | Unresectable | Tumor resection combined with partial small bowel resection | R0 |
20 | M/65 | Rectum | KIT E11 mut. | P | 400 | 12 | Abdominoperineal resection | Abdominoperineal resection (laparoscopic) | R0 |
21 | M/48 | Rectum | KIT E11 mut. | P | 400 | 7 | Abdominoperineal resection | Transanal minimally invasive surgery | R0 |
22 | F/32 | Rectum | KIT E11 mut. | P | 400 | 9 | Abdominoperineal resection | Sphincter-sparing resection | R0 |
23 | M/54 | Rectum | KIT E17 mut. | P | 400 | 12 | Abdominoperineal resection | Abdominoperineal resection (laparoscopic) | R0 |
24 | M/46 | Pelvic/retroperitoneal | KIT E11 mut. | R | 400 | 18 | Unresectable | Retroperitoneal tumor resection | R0 |
25 | M/40 | Pelvic/retroperitoneal | KIT E11 mut. | R | 400 | 7 | Unresectable | Pelvic tumor resection | R0 |