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Table 3 Clinicopathologic characteristics of mucosal gastric cancer compared with submucosal gastric cancer

From: Analysis of lymph node metastasis in early gastric cancer: a single institutional experience from China

Variables

Mucosal (n = 508)

Submucosal (n = 525)

P

Age, years

55.8 ± 11.3

57.9 ± 10.4

0.002

Sex, n (%)

 Male

314 (61.8)

354 (67.4)

0.059

 Female

194 (38.2)

171 (32.6)

 

Location, n (%)

 Upper

37 (7.3)

68 (13.0)

0.011

 Middle

104 (20.5)

100 (19.0)

 

 Lower

367 (72.2)

357 (68.0)

 

Tumor size, cm

2.0 ± 1.2

2.3 ± 1.1

< 0.001

Retrieved LN

24.5 ± 8.2

23.7 ± 8.1

0.100

LN metastasis, n (%)

 Negative

464 (91.3)

396 (75.4)

< 0.001

 Positive

44 (8.7)

129 (24.6)

 

Lymphovascular invasion, n (%)

 Negative

493 (97.0)

439 (83.6)

< 0.001

 Positive

15 (3.0)

86 (16.4)

 

Perineural invasion, n (%)

 Negative

508 (100.0)

493 (93.9)

< 0.001

 Positive

0 (0.0)

32 (6.1)

 

Differentiation, n (%)

 D-type

217 (42.7)

217 (41.3)

0.653

 UD-type

291 (57.3)

308 (58.7)

 

Lauren classificationa, n (%)

 Intestinal

213 (47.1)

262 (54.9)

0.003

 Diffuse

77 (17.0)

93 (19.5)

 

 Mixed

162 (35.9)

122 (25.6)

 
  1. D-type differentiated-type, LN lymph node, UD-type undifferentiated-type
  2. aThere are some patients with unknown information about the Lauren classification