Table 1 Univariate analysis of risk factors for lymph node metastasis in early gastric cancer
Variables | LN negative (n = 860) | LN positive (n = 173) | P |
|---|---|---|---|
Age, years | 57.4 ± 10.8 | 54.2 ± 11.3 | < 0.001 |
Sex, n (%) | |||
Male | 583 (87.3) | 85 (12.7) | < 0.001 |
Female | 277 (75.9) | 88 (24.1) | |
Location, n (%) | |||
Upper | 93 (85.6) | 12 (11.4) | 0.262 |
Middle | 166 (81.4) | 38 (18.6) | |
Lower | 601 (83.0) | 123 (17.0) | |
Tumor size, cm | 2.1 ± 1.1 | 2.5 ± 1.3 | < 0.001 |
Retrieved LN | 23.9 ± 7.9 | 25.1 ± 9.3 | 0.062 |
Invasion depth | |||
Mucosal | 464 (91.3) | 44 (8.7) | < 0.001 |
Submucosal | 396 (75.4) | 129 (24.6) | |
Lymphovascular invasion, n (%) | |||
Negative | 815 (87.4) | 117 (12.6) | < 0.001 |
Positive | 45 (44.6) | 56 (55.4) | |
Perineural invasion, n (%) | |||
Negative | 846 (84.5) | 155 (15.5) | < 0.001 |
Positive | 14 (43.7) | 18 (56.3) | |
Differentiation, n (%) | |||
D-type | 397 (91.5) | 37 (8.5) | < 0.001 |
UD-type | 463 (77.3) | 136 (22.7) | |
Lauren classificationa, n (%) | |||
Intestinal | 427 (89.9) | 48 (10.1) | < 0.001 |
Diffuse | 218 (76.8) | 66 (23.2) | |
Mixed | 127 (74.7) | 43 (25.3) | |