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Table 1 Univariate analysis of risk factors for lymph node metastasis in early gastric cancer

From: Analysis of lymph node metastasis in early gastric cancer: a single institutional experience from China

VariablesLN negative (n = 860)LN positive (n = 173)P
Age, years57.4 ± 10.854.2 ± 11.3< 0.001
Sex, n (%)
 Male583 (87.3)85 (12.7)< 0.001
 Female277 (75.9)88 (24.1) 
Location, n (%)
 Upper93 (85.6)12 (11.4)0.262
 Middle166 (81.4)38 (18.6) 
 Lower601 (83.0)123 (17.0) 
Tumor size, cm2.1 ± 1.12.5 ± 1.3< 0.001
Retrieved LN23.9 ± 7.925.1 ± 9.30.062
Invasion depth
 Mucosal464 (91.3)44 (8.7)< 0.001
 Submucosal396 (75.4)129 (24.6) 
Lymphovascular invasion, n (%)
 Negative815 (87.4)117 (12.6)< 0.001
 Positive45 (44.6)56 (55.4) 
Perineural invasion, n (%)
 Negative846 (84.5)155 (15.5)< 0.001
 Positive14 (43.7)18 (56.3) 
Differentiation, n (%)
 D-type397 (91.5)37 (8.5)< 0.001
 UD-type463 (77.3)136 (22.7) 
Lauren classificationa, n (%)
 Intestinal427 (89.9)48 (10.1)< 0.001
 Diffuse218 (76.8)66 (23.2) 
 Mixed127 (74.7)43 (25.3) 
  1. D-type differentiated-type, LN lymph node, UD-type undifferentiated-type
  2. aThere are some patients with unknown information about the Lauren classification