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Fig. 1 | World Journal of Surgical Oncology

Fig. 1

From: Salivary cortisol levels and anxiety in melanoma patients undergoing sentinel lymph node excision under local anesthesia versus general anesthesia: a prospective study

Fig. 1

Study design. Melanoma patients scheduled for SLNE were allocated into two groups: those receiving TLA and those receiving GA during surgery. Group assignment was based on patient preference. Saliva for cortisol measurements was collected on preoperative days (T1, T2), on the day of surgery (T3–T5), and 2 days after surgery (T6). In addition, patients had to complete psychological questionnaires at indicated time points. STAI, State-Trait Anxiety Inventory; HADS, Hospital Anxiety Depression Scale

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