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Table 3 Univariate and multivariate analysis of risk factors for delayed healing of perineal wound

From: Risk factors for delayed perineal wound healing and its impact on prolonged hospital stay after abdominoperineal resection

VariablesNo delayed healing
n = 143 (%)
Delayed healing
n = 86 (%)
PMultivariate
OR (95% CI)P
Age > 65 (years old)82 (57.3)58 (67.4)0.129  
Gender  0.170  
 Male96 (67.1)50 (58.1)   
 Female47 (32.9)36 (41.9)   
Hypertension59 (41.3)40 (46.5)0.437  
Diabetic mellitus21 (14.7)18 (20.9)0.223  
Congestive heart failure24 (16.8)14 (16.3)0.921  
COPD8 (5.6)2 (2.3)0.241  
Uremia6 (4.2)3 (3.5)0.790  
Liver cirrhosis3 (2.1)0 (0.0)0.176  
Smoking     
 Previous38 (26.6)23 (26.7)0.977  
 Current25 (17.5)13 (15.1)0.641  
BMI (kg/m2)     
 Underweight (< 18.5)5 (3.5)4 (4.7)0.595  
 Overweight (> 25)53 (37.1)33 (38.4)0.517  
Neoadjuvant radiotherapy41 (28.7)35 (40.7)0.0611.582 (0.889–2.816)0.119
Hypoalbuminemia (< 3.5 g/dL)15 (10.5)23 (26.7)0.001*2.962 (1.437–6.102)0.003*
Pre-op CEA > 5 ng/mL47 (34.3)32 (37.6)0.613  
Resection of other pelvic organ19 (13.3)13 (15.1)0.699  
Laparoscopic operation14 (9.8)14 (16.3)0.147  
Operation time > 240 min70 (49.0)45 (52.3)0.621  
Blood loss > 250 ml62 (43.4)41 (47.7)0.525  
  1. COPD chronic obstructive pulmonary disease, BMI body mass index, CEA carcinoembryonic antigen
  2. *Statistically significant, P < 0.05