Table 3 Univariate and multivariate analysis of risk factors for delayed healing of perineal wound
Variables | No delayed healing n = 143 (%) | Delayed healing n = 86 (%) | P | Multivariate | |
|---|---|---|---|---|---|
OR (95% CI) | P | ||||
Age > 65 (years old) | 82 (57.3) | 58 (67.4) | 0.129 | ||
Gender | 0.170 | ||||
Male | 96 (67.1) | 50 (58.1) | |||
Female | 47 (32.9) | 36 (41.9) | |||
Hypertension | 59 (41.3) | 40 (46.5) | 0.437 | ||
Diabetic mellitus | 21 (14.7) | 18 (20.9) | 0.223 | ||
Congestive heart failure | 24 (16.8) | 14 (16.3) | 0.921 | ||
COPD | 8 (5.6) | 2 (2.3) | 0.241 | ||
Uremia | 6 (4.2) | 3 (3.5) | 0.790 | ||
Liver cirrhosis | 3 (2.1) | 0 (0.0) | 0.176 | ||
Smoking | |||||
Previous | 38 (26.6) | 23 (26.7) | 0.977 | ||
Current | 25 (17.5) | 13 (15.1) | 0.641 | ||
BMI (kg/m2) | |||||
Underweight (< 18.5) | 5 (3.5) | 4 (4.7) | 0.595 | ||
Overweight (> 25) | 53 (37.1) | 33 (38.4) | 0.517 | ||
Neoadjuvant radiotherapy | 41 (28.7) | 35 (40.7) | 0.061 | 1.582 (0.889–2.816) | 0.119 |
Hypoalbuminemia (< 3.5 g/dL) | 15 (10.5) | 23 (26.7) | 0.001* | 2.962 (1.437–6.102) | 0.003* |
Pre-op CEA > 5 ng/mL | 47 (34.3) | 32 (37.6) | 0.613 | ||
Resection of other pelvic organ | 19 (13.3) | 13 (15.1) | 0.699 | ||
Laparoscopic operation | 14 (9.8) | 14 (16.3) | 0.147 | ||
Operation time > 240 min | 70 (49.0) | 45 (52.3) | 0.621 | ||
Blood loss > 250 ml | 62 (43.4) | 41 (47.7) | 0.525 | ||