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Table 1 Comparison of patients’ baseline characteristics between the three year groups

From: Chronological changes and trend of breast cancer clinics and pathology among Iranian women during 22 years from the largest breast cancer registry in Iran

Variables

 

Year diagnosis group

p value

  

1993–2005 (n = 688)

2006–2011 (n = 1871)

2012–2017 (n = 3020)

 

Sex—no. (%)

Male

3 (0.4)

18 (1.0)

19 (0.6)

0.18

 

Female

685 (99.6)

1853 (99.0)

3001 (99.3)

 

Education—no. (%)

Illiterate

48 (24.9)a

117 (18.0)b

306 (16.2)b

0.01

 

Primary school

53 (27.5)a

203 (31.3)a

529 (28.0)a

 
 

High school

65 (33.7)a

201 (31.0)a

647 (34.2)a

 
 

Collage education

27 (14.0)a

128 (22.7)a, b

408 (21.6)b

 

Job—no. (%)

Retired

40 (19.2)a

107 (14.6)a

185 (8.3)b

0.01

 

Stay at home

157 (75.5)a

563 (76.9)a

1811 (81.1)b

 
 

Governmental employee

11 (5.3)a

62 (8.5)a, b

237 (10.6)b

 

Marital status—no. (%)

Divorced

7 (3.3)a

15 (2.0)a

38 (1.7)a

0.01

 

Married

156 (73.9)a

587 (79.3)a, b

1840 (79.9)b

 
 

Single

48 (22.8)a

138 (18.7)b

414 (18.4)b

 

BMI—kg/m2

 

28.06 ± 4.99

27.60 ± 4.52

27.92 ± 4.90

0.225

Age of start menstruation—yrs

 

13.28 ± 1.41

13.39 ± 1.92

13.26 ± 1.94

0.250

Age of first pregnancy—yrs

 

20.79 ± 5.46

21.50 ± 6.83

21.63 ± 7.52

0.290

No. of abortions

 

1.52 ± 0.86

1.51 ± 0.88

1.57 ± 1.03

0.669

No. of children

 

4.02 ± 1.99a

3.55 ± 1.77b

3.36 ± 1.88b

<0.001

Duration of breast feeding—wks

 

68.03 ± 52.11a

59.12 ± 42.01b

57.55 ± 41.93b

0.006

Age of menopause—yrs

 

47.31 ± 4.73

47.76 ± 6.10

48.06 ± 5.41

0.208

Use of OCP—no. (%)

Yes

127 (60.2)a

406 (55.1)a, b

1189 (51.8)b

0.031

 

No

84 (39.8)a

331 (44.9)a, b

1105 (48.2)b

 

Use of HRT—no. (%)

Yes

4 (1.9)

9 (1.3)

36 (1.6)

0.72

 

No

204 (98.1)

708 (98.7)

2212 (98.4)

 

Cigarette use—no. (%)

Yes

1 (0.5)

4 (0.5)

26 (1.1)

0.278

 

No

207 (99.5)

739 (99.5)

2290 (98.9)

 

Waterpipe use—no. (%)

Yes

19 (9.1)

58 (7.8)

213 (9.2)

0.492

 

No

190 (90.9)

684 (92.2)

2091 (90.8)

 

Use of alcohol—no. (%)

Yes

0

1 (0.1)

3 (0.1)

0.872

 

No

207 (100)

739 (99.9)

2302 (99.9)

 

Physical activity—no. (%)

Yes

64 (30.8)a

310 (41.9)b

932 (40.3)b

0.01

 

No

144 (69.2)a

430 (58.1)b

1379 (59.7)b

 
  1. BMI, body mass index; OCP, oral contraceptive pill; HRT, hormone replacement therapy
  2. All plus-minus values are means and standard deviation, unless stated otherwise. Superscript alphabets represent the results of the post-hoc test, and accordingly different alphabets show significant difference between groups. “a” is statistically different from “b” and “c”, “b” is statistically different from “a” and “c”, and “c” is statistically different from “a” and “b”