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Table 1 Comparison of patients’ baseline characteristics between the three year groups

From: Chronological changes and trend of breast cancer clinics and pathology among Iranian women during 22 years from the largest breast cancer registry in Iran

Variables Year diagnosis groupp value
  1993–2005 (n = 688)2006–2011 (n = 1871)2012–2017 (n = 3020) 
Sex—no. (%)Male3 (0.4)18 (1.0)19 (0.6)0.18
 Female685 (99.6)1853 (99.0)3001 (99.3) 
Education—no. (%)Illiterate48 (24.9)a117 (18.0)b306 (16.2)b0.01
 Primary school53 (27.5)a203 (31.3)a529 (28.0)a 
 High school65 (33.7)a201 (31.0)a647 (34.2)a 
 Collage education27 (14.0)a128 (22.7)a, b408 (21.6)b 
Job—no. (%)Retired40 (19.2)a107 (14.6)a185 (8.3)b0.01
 Stay at home157 (75.5)a563 (76.9)a1811 (81.1)b 
 Governmental employee11 (5.3)a62 (8.5)a, b237 (10.6)b 
Marital status—no. (%)Divorced7 (3.3)a15 (2.0)a38 (1.7)a0.01
 Married156 (73.9)a587 (79.3)a, b1840 (79.9)b 
 Single48 (22.8)a138 (18.7)b414 (18.4)b 
BMI—kg/m2 28.06 ± 4.9927.60 ± 4.5227.92 ± 4.900.225
Age of start menstruation—yrs 13.28 ± 1.4113.39 ± 1.9213.26 ± 1.940.250
Age of first pregnancy—yrs 20.79 ± 5.4621.50 ± 6.8321.63 ± 7.520.290
No. of abortions 1.52 ± 0.861.51 ± 0.881.57 ± 1.030.669
No. of children 4.02 ± 1.99a3.55 ± 1.77b3.36 ± 1.88b<0.001
Duration of breast feeding—wks 68.03 ± 52.11a59.12 ± 42.01b57.55 ± 41.93b0.006
Age of menopause—yrs 47.31 ± 4.7347.76 ± 6.1048.06 ± 5.410.208
Use of OCP—no. (%)Yes127 (60.2)a406 (55.1)a, b1189 (51.8)b0.031
 No84 (39.8)a331 (44.9)a, b1105 (48.2)b 
Use of HRT—no. (%)Yes4 (1.9)9 (1.3)36 (1.6)0.72
 No204 (98.1)708 (98.7)2212 (98.4) 
Cigarette use—no. (%)Yes1 (0.5)4 (0.5)26 (1.1)0.278
 No207 (99.5)739 (99.5)2290 (98.9) 
Waterpipe use—no. (%)Yes19 (9.1)58 (7.8)213 (9.2)0.492
 No190 (90.9)684 (92.2)2091 (90.8) 
Use of alcohol—no. (%)Yes01 (0.1)3 (0.1)0.872
 No207 (100)739 (99.9)2302 (99.9) 
Physical activity—no. (%)Yes64 (30.8)a310 (41.9)b932 (40.3)b0.01
 No144 (69.2)a430 (58.1)b1379 (59.7)b 
  1. BMI, body mass index; OCP, oral contraceptive pill; HRT, hormone replacement therapy
  2. All plus-minus values are means and standard deviation, unless stated otherwise. Superscript alphabets represent the results of the post-hoc test, and accordingly different alphabets show significant difference between groups. “a” is statistically different from “b” and “c”, “b” is statistically different from “a” and “c”, and “c” is statistically different from “a” and “b”