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Table 3 Univariate and multivariate analysis for variables associated with pre-SLR

From: Association of pre-surgery to pre-radiotherapy lymphocyte counts ratio with disease-free survival in rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy

Clinical factors

Univariate analysis

Multivariable analysis

HR

95% CI

p

HR

95% CI

p

Age

(≤ 60 vs > 60)

1.257

0.333–4.742

0.735

   

Sex

(F vs M)

2.062

0.492–8.654

0.322

   

N status

(N+ vs N−)

1.250

0.299–5.230

0.760

   

CEA

(> 5.0 vs ≤ 5.0)

0.606

0.158–2.319

0.464

   

Pre-RTL

(L vs H)

8.000

1.686–37.981

0.009

   

V5

(L vs H)

4.469

1.054–18.938

0.042

   

V10

(L vs H)

2.041

0.521–7.999

0.306

   

V20

(L vs H)

3.361

0.823–13.722

0.091

   

V30

(L vs H)

5.760

1.317–25.187

0.020

5.760

1.317–25.187

0.020

V40

(L vs H)

3.361

0.823–13.722

0.091

   

Dmean

(L vs H)

3.361

0.823–13.722

0.091

   
  1. HR, hazard ratio; CI, confidence interval; F, female; M, male; CEA, carcino-embryonic antigen; N, lymph node; N+, lymph node positive; N−, lymph node negtive; pre-SL, absolute lymphocyte counts before surgery; pre-RTL, absolute lymphocyte counts before concurrent chemoradiotherapy; n, no; y, yes; L, low; H, high