Over-expression of Nav1.6 channels is associated with lymph node metastases in colorectal cancer

Table 2 Two-tailed t test analysis of the correlation between the upregulation of different sodium channel subtypes and lymph node metastasis in CRC tissues

Nav channel	Lymph node metastasis CRC	Non-lymph node metastasis CRC	T	P
Nav 1.1	3.19 ± 2.91	2.05 ± 1.96	2.304	0.023
Nav 1.2	2.07 ± 2.37	1.97 ± 1.96	0.213	0.832
Nav 1.3	0.34 ± 0.45	0.41 ± 0.52	− 0.682	0.497
Nav 1.4	3.08 ± 2.90	2.23 ± 2.21	1.630	0.106
Nav 1.5	1.64 ± 1.34	1.17 ± 1.186	1.811	0.073
Nav 1.6	3.63 ± 3.21	2.13 ± 1.96	2.534	0.014
Nav 1.7	1.80 ± 1.76	2.13 ± 2.48	− 0.683	0.496
Nav 1.8	3.11 ± 2.72	2.59 ± 1.94	1.098	0.275
Nav 1.9	1.66 ± 1.48	1.86 ± 1.70	− 0.603	0.548

The independent sample t test in SPSS20.0 was used to determine whether lymph node metastasis was a grouping variable, and the expression of the sodium ion channel subtype was a test variable. When the sig value of the Levene test is greater than 0.05, the T value and the P value are obtained by assuming the variance is equal. When the sig value of the Levene test is less than 0.05, the T value and the P value are obtained by assuming that the variances are not equal. An obtained P value < 0.05 is indicated in italic

ISSN: 1477-7819