Fig. 4
From: Over-expression of Nav1.6 channels is associated with lymph node metastases in colorectal cancer
Association of known markers of lymph node metastasis and infiltration with Nav1.6. a, b Quantitative PCR analysis of mRNA expression levels for lymphocyte infiltration- and lymph node metastasis-related molecular biomarkers in 97 CRC tissues. c Proportion of patients with a high expression of lymphocyte infiltration- and lymph node metastasis-related molecular biomarkers in 97 CRC patients. d Two-tailed t test analysis of the correlation between the upregulation of CCR2 and CCR4 and lymph node metastasis in CRC tissues. The independent sample t test in SPSS20.0 was used to determine whether nav1.6 was highly expressed as a grouping variable and CCR2\CCR4 as a test variable. When the sig value of the Levene test is greater than 0.05, the T value and the P value are obtained by assuming the variance is equal. When the sig value of the Levene test is less than 0.05, the T value and the P value are obtained by assuming that the variances are not equal