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Table 4 Evaluation of risks for colorectal cancer

From: High expression of FABP4 and FABP6 in patients with colorectal cancer

Variable

Unadjusted

P value

Adjusted

P value

OR (95% CI)

OR (95% CI)

BMI (kg/m2)

1.499 (0.710, 3.166)

0.289

---

---

WHR

2.138 (1.002, 4.584)

0.037

2.084 (0.949, 4.578)

0.047

SBP (mmHg)

1.286 (0.815, 1.641)

0.055

1.258 (0.565, 2.802)

0.575

DBP (mmHg)

1.372 (0.993, 1.707)

0.051

1.034 (0.856, 1.413)

0.064

TCH (mmol/L)

0.522 (0.209, 1.307)

0.165

---

---

TG (mmol/L)

0.927 (0.508, 1.692)

0.805

---

---

LDL-C (mmol/L)

4.301 (3.271, 5.432)

< 0.001

4.197 (3.144, 5.393)

< 0.001

HDL-C (mmol/L)

0.078 (0.028, 0.218)

< 0.001

0.124 (0.057, 0.274)

< 0.001

FPG (mmol/L)

0.979 (0.274, 3.493)

0.974

---

---

FABP4 (pg/ml)

2.141 (1.352, 3.074)

< 0.001

1.916 (1.340, 2.492)

< 0.001

FABP6 (pg/ml)

2.767 (1.517, 3.826)

< 0.001

2.162 (1.046,1.078)

< 0.001

CEA (ng/ml)

1.940 (1.038, 3.479)

0.026

1.713 (1.026, 3.236)

0.040

CA19-9 (U/ml)

3.516 (0.938, 6.186)

0.062

---

---

Family history of CRC

7.298 (5.210, 9.747)

< 0.001

5.119(3.940, 7.569)

< 0.001

  1. Adjusted for WHR, SBP, DBP, LDL-C, HDL-C, CEA, family history of CRC; OR odd ratio, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, WHR waist:hip ratio, TCH total cholesterol, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, FPG fasting plasma glucose, FABP4 fatty acid-binding proteins 4, FABP6 fatty acid-binding proteins 6, CEA carcinoembryoni, CA19-9 carbohydrate antigen 19-9