Skip to main content

Table 1 Comparison of clinical parameters and biochemical indicators between CRC group and control group [(\( \overline{x} \) ± s, n (%)]

From: High expression of FABP4 and FABP6 in patients with colorectal cancer

Variable CRC group
(n = 100)
Pa value Control group (n = 100) Pb value
Before surgery After surgery
Age (years) 55.50 ± 8.87 55.50 ± 8.87 NS 53.31 ± 10.58 NS
Sex
 Male 64 (64) 64 (64) NS 36 (36) NS
 Female 53 (53) 53 (53)   47 (47)  
Smokers
 Current 21 (21) 21 (21) NS 30 (30) NS
 Ex 10 (10) 10 (10) NS 7 (7) NS
Alcohol 40 (40) 40 (40) NS 33 (33) NS
NSAIDs 16 (16) 16 (16) NS 10 (10) NS
Diabetes 6 6 NS 5 NS
Family history of CRC 7 (7) 7 (7) NS 1 (1) 0.030
BMI (kg/m2) 23.49 ± 2.73 23.42 ± 2.66 NS 22.81 ± 2.78 NS
WC (cm) 84.8 ± 8.6 84.6 ± 8.7 NS 83.5 ± 7.5 0.236
WHR 0.89 ± 0.07 0.89 ± 0.09 NS 0.87 ± 0.07 0.043
SBP (mmHg) 127 ± 16 126 ± 17 NS 128 ± 20 0.940
DBP (mmHg) 79 ± 11 80 ± 12 NS 82 ± 13 0.055
TCH (mmol/L) 4.77 ± 0.92 4.79 ± 0.89 NS 4.37 ± 0.90 0.003
TG (mmol/L) 1.59 ± 0.95 1.57 ± 0.87 NS 1.46 ± 0.80 0.287
LDL-C (mmol/L) 2.89 ± 0.97 2.88 ± 0.93 NS 2.53 ± 0.50 0.001
HDL-C (mmol/L) 1.17 ± 0.49 1.16 ± 0.52 NS 1.65 ± 0.14 0.006
FPG (mmol/L) 6.17 ± 4.45 6.34 ± 4.72 NS 5.50 ± 1.16 NS
FABP4 (pg/ml) 302.24 ± 56.58 268.08 ± 33.92 < 0.001 191.97 ± 53.49 < 0.001
FABP6 (pg/ml) 411.86 ± 83.25 354.64 ± 41.79 < 0.001 289.66 ± 48.57 < 0.001
CEA (ng/ml) 8.88 ± 1.26 6.72 ± 1.32 0.029 5.08 ± 0.81 0.001
CA-199 (U/ml) 14.50 ± 3.39 12.40 ± 4.36 0.048 11.02 ± 2.41 0.004
  1. Abbreviations: NSAID non-steroid anti-inflammatory drug, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, WC waist circumference, WHR waist:hip ratio, TCH total cholesterol, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, FPG fasting plasma glucose, FABP4 fatty acid-binding proteins 4, FABP6 fatty acid-binding proteins 6, CEA carcinoembryonic, CA19-9 carbohydrate antigen 19-9, NS non-significant Intergroup comparisions, Pa after surgery vs before surgery, Pb control group vs CRC group before surgery)