Table 1 Association between the expression of S100A4 and serum CA19.9 level and clinicopathological characteristics in PC n (%)
Clinicopathological parameter | Cases (n) | S100A4 expression | P value | Serum CA19.9 level | P value | ||
|---|---|---|---|---|---|---|---|
Positive (+) | Negative (−) | High (+) | Normal (−) | ||||
Gender | 0.917 | 0.489 | |||||
Male | 75 | 56 (58.3) | 19 (59.4) | 68 (59.6) | 7 (50.0) | ||
Female | 53 | 40 (41.7) | 13 (40.6) | 46 (40.4) | 7 (50.0) | ||
Age (year) | 0.355 | 0.203 | |||||
< 60 | 57 | 45 (46.9) | 12 (37.5) | 53 (46.5) | 4 (28.6) | ||
≥ 60 | 71 | 51 (53.1) | 20 (62.5) | 61 (53.5) | 10 (71.4) | ||
Tumor size (cm) | 0.028 | 0.699 | |||||
≤ 2 | 5 | 3 (3.1) | 2 (6.3) | 5 (4.4) | 0 | ||
2–4 | 83 | 57 (59.4) | 26 (81.3) | 74 (64.9) | 9 (64.3) | ||
>4 | 40 | 36 (37.5) | 4 (12.5) | 35 (30.7) | 5 (35.7) | ||
Tumor location | 0.217 | 0.521 | |||||
Head | 72 | 51 (53.1) | 21 (65.6) | 63 (55.3) | 9 (64.3) | ||
Body/tail | 56 | 45 (46.9) | 11 (34.4) | 51 (44.7) | 5 (35.7) | ||
Differentiation | 0.007 | 0.000 | |||||
High | 36 | 22 (22.9) | 14 (43.8) | 26 (22.8) | 10 (71.4) | ||
Middle | 66 | 49 (51.0) | 17 (53.1) | 62 (54.4) | 4 (28.6) | ||
Low | 26 | 25 (26.0) | 1 (3.1) | 26 (22.8) | 0 | ||
TNM stage | 0.000 | 0.248 | |||||
I | 11 | 6 (6.3) | 5 (15.6) | 10 (8.8) | 1 (7.1) | ||
II | 47 | 26 (27.1) | 21 (65.6) | 39 (34.2) | 8 (57.1) | ||
III | 52 | 46 (47.9) | 6 (18.8) | 47 (41.2) | 5 (35.7) | ||
IV | 18 | 18 (18.8) | 0 | 18 (15.8) | 0 | ||
Distant metastasis | 0.076 | 0.194 | |||||
Present | 26 | 23 (24.0) | 3 (9.4) | 25 (21.9) | 1 (7.1) | ||
Absent | 102 | 73 (76.0) | 29 (90.6) | 89 (78.1) | 13 (92.9) | ||
Lymph node metastasis | 0.025 | 0.003 | |||||
Present | 66 | 55 (57.3) | 11 (34.4) | 64 (56.1) | 2 (14.3) | ||
Absent | 62 | 41 (42.7) | 21 (65.6) | 50 (43.9) | 12 (85.7) | ||