Comparison of efficacy of robotic surgery, laparoscopy, and laparotomy in the treatment of ovarian cancer: a meta-analysis

Table 4 Results of the meta-analysis

Variable	Sample size		Test of association			Model	Test of heterogeneity^a,b			Egger’s test^c
Variable	N1	N2	WMD/OR (95% CI)	Z	P	Model	Q	P	I² (%)	t	P
R vs. L
EBL	96	79	− 55.0871 [− 139.0087; 28.8345]	1.29	0.1983	R	8.83	0.07	54.7	0.3887	0.7234
LHS	96	79	− 1.4296[− 3.5326; 0.6734]	1.33	0.1827	R	13.06	0.01	69.4	0.9334	0.4195
OT	104	90	− 0.8561[− 46.3735; 44.6612]	0.04	0.9706	R	13.4	< 0.01	70.2	0.7602	0.5024
PC	144	166	1.4541 [0.6502; 3.2516]	0.91	0.3619	F	5.34	0.38	6.3	1.5330	0.2001
PN	78	58	− 0.5664 [− 3.1615; 2.0288]	0.43	0.6688	F	2.78	0.25	28.2	0.7882	0.5751
PR	26	32	0.2387 [0.0445; 1.2792]	1.67	0.0944	F	1.34	0.25	25.5	NA	NA
OS rate	60	44	2.2000 [0.0842; 57.4835]	0.47	0.6360	NA	NA	NA	NA	NA	NA
DFS rate	60	44	1.6909 [0.2572; 11.1175]	0.55	0.5850	F	0.05	0.83	0.0	NA	NA
R vs. O
EBL	125	274	− 521.7027 [− 809.7816; − 233.6238]	3.55	0.0004	R	82.54	< 0.01	93.9	1.1403	0.3178
LHS	159	274	− 5.2225 [− 6.1485; − 4.2965]	11.05	< 0.0001	F	8.36	0.14	40.2	0.1786	0.8669
OT	151	259	9.8527 [− 57.0904; 76.7958]	0.29	0.7730	R	59.75	< 0.01	93.3	0.5645	0.6119
PC	159	274	0.4710 [0.2537; 0.8747]	2.38	0.0171	F	1.77	0.88	0.0	6.8290	0.0024
PN	141	226	0.0048 [− 1.9418; 1.9514]	<0.01	0.9962	F	4.77	0.19	37.1	0.2131	0.8510
PR	73	59	0.8506 [0.3356; 2.1562]	0.34	0.7332	F	1.71	0.19	41.7	NA	NA
OS rate	107	99	6.4355 [1.6722; 24.7678]	2.71	0.0070	F	0.09	0.76	0.0	NA	NA

WMD weighted mean difference, OR odds ratio, CI confidence interval, EBL estimated blood loss, LHS length of hospital stay, OT operating time, PC postoperative complication, PN pelvic nodes, PR postoperative recurrence, OS overall survival, DFS disease-free survival, NA data are not available
^aRandom effects model was used when the P for heterogeneity test < 0.05; otherwise, the fixed effect model was used
^bP < 0.05 is considered statistically significant for Q test
^cEgger’s test to evaluate publication bias, P < 0.05 is considered statistically significant

ISSN: 1477-7819