Table 2 Toxicity profiles
Toxicity | Grade (CTCAE v4.0) | |||||
|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | All | G3 | |
Hematological | ||||||
Leukopenia | 1 | 12 | 3 | 0 | 16 | 3 |
Neutropenia | 0 | 2 | 0 | 0 | 2 | 0 |
Anemia | 4 | 2 | 1 | 0 | 7 | 1 |
Thrombocytopenia | 0 | 1 | 0 | 0 | 1 | 0 |
Non-hematological | ||||||
Elevated creatinine | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated AST/ALT | 2 | 0 | 0 | 0 | 2 | 0 |
Hyperbilirubinemia | 0 | 0 | 0 | 0 | 0 | 0 |
Hyponatremia | 2 | 0 | 0 | 0 | 2 | 0 |
Alopecia | 0 | 0 | 0 | 0 | 0 | 0 |
Anorexia | 3 | 2 | 2 | 0 | 7 | 2 |
Constipation | 0 | 0 | 0 | 0 | 0 | 0 |
Diarrhea | 0 | 0 | 0 | 0 | 0 | 0 |
Edema | 0 | 0 | 0 | 0 | 0 | 0 |
Fever | 0 | 0 | 0 | 0 | 0 | 0 |
Nausea | 0 | 0 | 0 | 0 | 0 | 0 |
Rash | 0 | 0 | 0 | 0 | 0 | 0 |
Stomatitis | 0 | 0 | 0 | 0 | 0 | 0 |
Vomiting | 0 | 0 | 0 | 0 | 0 | 0 |