Table 3 Multivariate analyses of prognostic factors
Demographic or characteristic | 7th edition | 8th edition | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Age, years | ||||
< 70 | 1 | 1 | ||
≥ 70 | 1.32 (1.14–1.52) | < 0.001 | 1.35 (1.16–1.55) | < 0.001 |
Sex | ||||
Male | 1 | 1 | ||
Female | 1.04 (0.90–1.20) | 0.572 | 1.04 (0.90–1.20) | 0.574 |
Race | ||||
White | 1 | 1 | ||
Black | 0.91 (0.69–1.19) | 0.479 | 0.89 (0.68–1.17) | 0.402 |
Others | 0.80 (0.61–1.04) | 0.094 | 0.79 (0.60–1.03) | 0.083 |
Location | ||||
Head | 1 | 1 | ||
Others | 1.10 (0.94–1.27) | 0.247 | 1.08 (0.93–1.26) | 0.290 |
Grade | ||||
Low, intermediate | 1 | 1 | ||
High | 1.24 (1.03–1.49) | 0.027 | 1.20 (1.00–1.45) | 0.056 |
Unknown | 1.15 (0.97–1.36) | 0.111 | 1.10 (0.93–1.31) | 0.253 |
Stage | ||||
IA | 1 | 1 | ||
IB | 1.48 (0.94–2.31) | 0.087 | 1.48 (1.02–2.15) | 0.040 |
IIA | 2.33 (1.54–3.51) | < 0.001 | 1.26 (0.86–1.85) | 0.232 |
IIB | 4.31 (2.94–6.31) | < 0.001 | 2.91 (2.09–4.05) | < 0.001 |
III | 6.08 (3.76–9.83) | < 0.001 | 4.14 (2.94–5.82) | < 0.001 |
IV | 11.81 (8.13–17.14) | < 0.001 | 8.95 (6.58–12.18) | < 0.001 |
C-index | 0.75 | < 0.001 | 0.75 | < 0.001 |