Table 1 The 7th and 8th editions of the American Joint Cancer Committee (AJCC) staging definitions for invasive intraductal papillary mucinous neoplasms (IPMN) with cross-tabulation of stage distributions
7th edition | 8th edition | ||||||
|---|---|---|---|---|---|---|---|
T1 | Limited to the pancreas, ≤ 2 cm in greatest dimension | T1 | Maximum tumor diameter ≤ 2 cm | ||||
T2 | Limited to the pancreas, > 2 cm in greatest dimension | T2 | Maximum tumor diameter > 2 ≤ 4 cm | ||||
T3 | Beyond the pancreas but without involvement of the celiac axis or the superior mesenteric artery | T3 | Maximum tumor diameter > 4 cm | ||||
T4 | Involvement of celiac axis or the superior mesenteric artery (unresectable tumor) | T4 | Involvement of celiac axis or the superior mesenteric artery (unresectable tumor) | ||||
N0 | No regional lymph node metastasis | N0 | No regional lymph node metastasis | ||||
N1 | Regional lymph node metastasis | N1 | Metastasis in 1–3 regional lymph nodes | ||||
N2 | Metastasis in ≥ 4 regional lymph nodes | ||||||
M0 | No distant metastasis | M0 | No distant metastasis | ||||
M1 | Distant metastasis | M1 | Distant metastasis | ||||
Stage | T | N | M | Stage | T | N | M |
IA | T1 | N0 | M0 | IA | T1 | N0 | M0 |
IB | T2 | N0 | M0 | IB | T2 | N0 | M0 |
IIA | T3 | N0 | M0 | IIA | T3 | N0 | M0 |
IIB | T1–3 | N1 | M0 | IIB | T1–3 | N1 | M0 |
III | T4 | Any N | M0 | III | Any T | N2 | M0 |
T4 | Any N | M0 | |||||
IV | Any T | Any N | M1 | IV | Any T | Any N | M1 |
Edition | 8th | ||||||
IA | IB | IIA | IIB | III | IV | ||
7th | IA | 124 | 0 | 0 | 0 | 0 | 0 |
IB | 0 | 64 | 69 | 0 | 0 | 0 | |
IIA | 31 | 80 | 79 | 0 | 0 | 0 | |
IIB | 0 | 0 | 0 | 207 | 107 | 0 | |
III | 0 | 0 | 0 | 0 | 45 | 0 | |
IV | 0 | 0 | 0 | 0 | 0 | 410 | |