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Table 3 Results of blood biochemistry and coagulation function after operation

From: Effect of the intermittent Pringle maneuver on liver damage after hepatectomy: a retrospective cohort study

 

Non IPM

IPM

p value

First day after operation

 WBC

11.38 (9.05–14.08)

12.15 (9.85–15.3)

0.2386

 NLR

88.08 ± 3.68

87.33 ± 4.12

0.2307

 PLT

132 (105–168)

152 (114–210)

0.0381

 ALT

242.5 (129–336)

157.1 (98.2–384.3)

0.1709

 AST

254 (171–418)

208.8 (126.05–400.55)

0.1148

 ALB

32.48 ± 5.11

32.24 ± 6.05

0.7739

 TB

25.8 (17.5–40.9)

22.4 (15.7–33)

0.07

 PT

15.3 (14.3–17)

14.3 (13.5–15.8)

0.0195

 APTT

36.3 (32–43.4)

33.2 (28.6–38.7)

0.0071

 D-Dimer

2.92 (0.83–4.46)

3.765 (2.06–4.85)

0.1478

Third day after operation

 WBC

8.43 (5.78–10.59)

8.39 (6.47–10.84)

0.7004

 NLR

83.51 ± 5.3

80.5 ± 5.91

0.0057

 PLT

106.5 (74–158)

126 (100–167)

0.075

 ALT

133.9 (92–229.8)

104.1 (71–245)

0.2797

 AST

86 (67–132)

89 (64–140.4)

0.7739

 ALB

37.84 ± 5.09

37.08 ± 5.43

0.4332

 TB

22.7 (15.5–37.5)

26.05 (17.4–34.7)

0.6339

 PT

15.8 ± 3

14.9 ± 2.4

0.2071

 APTT

40.8 (33.4–52.4)

38.15 (32.6–42.9)

0.1275

 D-Dimer

3.84 (0.893–6.38)

4.65 (2.8–9.1)

0.1136

Fifth day after operation

 WBC

7.89 ± 3.05

8.05 ± 2.81

0.8301

 NLR

75.37 ± 8.86

72.98 ± 6.47

0.2143

 PLT

110.5 (72–176)

148 (119–198)

0.0739

 ALT

74.5 (53–104)

87 (59–139)

0.3716

 AST

50 (35–62)

52.1 (33–71)

0.5623

 ALB

36.2 ± 4.35

37.57 ± 4.24

0.2176

 TB

24.05 (13.7–32.8)

25.6 (18.4–33.6)

0.807

 PT

15.8 (14.05–17.65)

14.8 (13.1–16)

0.2038

 APTT

40.85 (34.35–48.95)

37.4 (30.9–38.8)

0.0526

 D-Dimer

5.5 (1.15–9.53)

9.62 (1.08–14.2)

0.3496

Seventh day after operation

 WBC

7.69 (7.08–11.19)

8.28 (7.39–12.04)

0.529

 NLR

70.89 ± 7.01

69.82 ± 8.18

0.6239

 PLT

178.11 ± 56.26

192.69 ± 98.42

0.5614

 ALT

49 (44–80)

55 (42–100)

0.5803

 AST

32 (23–49)

38.1 (29–53.9)

0.2185

 ALB

36.23 ± 4.37

35.91 ± 3.52

0.7621

 TB

19.5 (15.1–51.7)

21.1 (16.1–32.3)

0.9008

 PT

14.45 (13.6–17.25)

15 (13.6–16.6)

0.9422

 APTT

35.8 (29.7–46.85)

32.2 (29.7–61)

0.8283

 D-Dimer

5.715 (1.42–13.31)

7.41 (0.748–10.93)

0.665

Discharge from hospital

 WBC

6.35 ± 2.66

6.49 ± 2.27

0.7368

 NLR

67.56 ± 9.15

67.09 ± 7.5

0.7466

 PLT

184.5 (128–249)

178 (126–223)

0.5397

 ALT

46 (35–61)

48.8 (32.1–65.9)

0.2943

 AST

35 (25–46)

36.6 (28.1–51)

0.2819

 ALB

37.5 (33–40.8)

35.5 (31.9–37.9)

0.0303

 TB

16.4 (13–25.5)

16.7(11.9–25.2)

0.8516

 PT

13.05 (12.2–14.9)

13.1(12.2–14.1)

0.9695

 APTT

28.8 (27.4–34.8)

30.45 (28.5–35)

0.3497

 D-Dimer

8.67 ± 5.91

9.54 ± 5.14

0.7053

  1. Abbreviations: WBC white blood cell, NLR neutrophil to lymphocyte ratio, PLT platelet, ALT alanine transaminase, AST aspartate transaminase, ALB albumin, TB total bilirubin, PT prothrombin time, APTT activated partial thrombin time
  2. Footnote: Normal distribution quantitative data is expressed as mean ± standard deviation and compare the group comparison using analysis of variance; non-distribution data is expressed as median and quartile and compare the group comparison using Kruskal-Wallis test