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Table 1 Comparison of clinicopathological characteristics according to the number of LNM risk factors in patients whose tumors did not meet the criteria for endoscopic resection

From: Validity of additional surgical resection by comparing the operative risk with the stratified lymph node metastatic risk in patients with early gastric cancer after endoscopic submucosal dissection

  n Total number of items p value
0/1 2 3 4
Total 861 396 305 124 36  
Age, mean ± SD (years) 65.77 (11.06) 64.69 (11.36) 66.14 (10.72) 68.01 (10.84) 66.72 (10.30) 0.024
Sex, n (%)
 Male 579 (67.2) 253 (63.9) 220 (72.1) 85 (68.5) 21 (58.3) 0.081
 Female 282 (32.8) 143 (36.1) 85 (27.9) 39 (31.5) 15 (41.7)  
 Tumor size, mean ± SD (mm) 34.47 (20.54) 28.71 (17.78) 35.14 (20.35) 45.47 (19.54) 54.31 (25.37) < 0.001
Depth of tumor, n (%)
 M 317 (36.8) 237 (59.8) 78 (25.6) 2 (1.6) 0 (0) < 0.001
 SM1 144 (16.7) 118 (29.8) 17 (5.6) 9 (7.3) 0 (0)
 SM2 400 (46.5) 41 (10.4) 210 (68.9) 113 (91.1) 36 (100)
Histological type, n (%)
 Differentiated 359 (41.7) 169 (42.7) 142 (46.6) 48 (38.7) 0 (0) < 0.001
 Undifferentiated 502 (58.3) 227 (57.3) 163 (53.4) 76 (61.3) 36 (100)  
Lymphatic invasion, n (%)
 Negative 605 (70.3) 365 (92.2) 196 (64.3) 41 (33.1) 3 (8.3) < 0.001
 Positive 256 (29.7) 31 (7.8) 109 (35.7) 83 (66.9) 33 (91.7)  
Venous invasion, n (%)
 Negative 706 (82.0) 385 (97.2) 227 (74.4) 71 (57.3) 23 (63.9) < 0.001
 Positive 155 (18.0) 11 (2.8) 78 (25.6) 53 (42.7) 13 (36.1)  
Ulceration (scar), n (%)
 Negative 196 (22.8) 104 (26.3) 72 (23.6) 20 (16.1) 0 (0) 0.001
 Positive 665 (77.2) 292 (73.7) 233 (76.4) 104 (83.9) 36 (100)  
Preoperative ERM/ESD, n (%)
 Negative 743 (86.3) 337 (85.1) 256 (83.9) 114 (91.9) 36 (100) 0.012
 Positive 118 (13.7) 59 (14.9) 49 (16.1) 10 (8.1) 0 (0)