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Table 4 Univariate and multivariate analyses of predictors of overall survival

From: High-Mobility Group Box 1 expression predicts survival of patients after resection of adenocarcinoma of the ampulla of Vater

Univariate analysis     Multivariate analysis  
Variable HR 95% CI P value HR 95% CI P value
Age (60 ≤) 0.62 0.26–1.50 0.29
Sex (male) 1.40 0.61–3.22 0.42
Type of pancreatectomy (PD) 1.43 0.63–3.22 0.39
Node dissection (D1) 1.87 0.83–4.23 0.19
Operative time (480 min ≤) 0.97 0.42–2.20 0.93
Blood loss (800 ml ≤) 3.46 1.28–9.34 0.014 1.88 0.60–5.91 0.28
Transfusion (yes) 3.21 1.44–7.17 0.004 3.13 1.26–7.78 0.014
Morbidity (grade IIIa) 0.98 0.44–2.19 0.96
Tumor diameter (20 mm ≤) 1.12 0.47–2.65 0.80
Histological type (moderate or poor) 1.93 0.86–4.32 0.11
T stage (T2, T3a) 2.57 1.05–6.25 0.038 1.31 0.47–3.63 0.60
N stage (N1, N2) 9.12 3.53–23.57 < 0.001 7.43 2.83–19.54 < 0.001
HMGB1 expression (High) 2.48 1.09–5.66 0.030 3.54 1.37–9.16 0.009
Adjuvant chemotherapy (−) 0.70 0.30–1.64 0.42