Table 3 95% confidence intervals Cox regression univariate and multivariate analysis of risk factors expressed as hazard ratios for local recurrence in 150 patients

Gender (male)

1.14

0.44–3.00

0.79

Age (≤ 65 years)

1.23

0.47–3.23

0.68

BMI (≤ 25 kg/m²)

0.56

0.19–1.64

0.29

Tumor ≤ 6 cm distance from anal verge

3.52

1.30–9.56

0.01

3.33

1.11–9.98

0.03

Preoperative short-course radiotherapy

0.65

0.25–1.67

0.37

0.58

0.22-1.55

0.28

APE compared to AR operation

1.19

0.34–4.16

0.78

Mucinous histology

3.99

1.47–10.80

0.006

0.60

0.60–5.92

0.28

Involved lateral margin

7.90

2.75–22.74

< 0.001

6.40

2.01–20.36

0.002

Tumor perforation

8.31

2.70–25.53

< 0.001

Invasion of vessels/nerves/lymphatics

2.43

0.93–6.33

0.07

Early anastomotic complication

2.44

0.70–8.49

0.16

Grade 1–2/3–4

1.57

0.45–5.53

0.48