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Table 3 95% confidence intervals Cox regression univariate and multivariate analysis of risk factors expressed as hazard ratios for local recurrence in 150 patients

From: Is there a need for neoadjuvant short-course radiotherapy in T3 rectal cancer with positive lymph node involvement? A single-center retrospective cohort study

Variable Cox regression univariate analysis Cox regression multivariate analysis
HR 95% Cl p HR 95% Cl p
Gender (male) 1.14 0.44–3.00 0.79  
Age (≤ 65 years) 1.23 0.47–3.23 0.68
BMI (≤ 25 kg/m2) 0.56 0.19–1.64 0.29
Tumor ≤ 6 cm distance from anal verge 3.52 1.30–9.56 0.01 3.33 1.11–9.98 0.03
Preoperative short-course radiotherapy 0.65 0.25–1.67 0.37 0.58 0.22-1.55 0.28
APE compared to AR operation 1.19 0.34–4.16 0.78  
Mucinous histology 3.99 1.47–10.80 0.006 0.60 0.60–5.92 0.28
Involved lateral margin 7.90 2.75–22.74 < 0.001 6.40 2.01–20.36 0.002
Tumor perforation 8.31 2.70–25.53 < 0.001  
Invasion of vessels/nerves/lymphatics 2.43 0.93–6.33 0.07
Early anastomotic complication 2.44 0.70–8.49 0.16
Grade 1–2/3–4 1.57 0.45–5.53 0.48
  1. HR hazard ratio, CI 95% confidence interval, BMI body mass index, AR anterior resection (included Hartmann’s procedure), APE abdominoperineal excision