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Table 3 Microorganisms in seroma cultures performed with a conventional method and with aerobic and anaerobic blood culture bottles. Each positive seroma culture was classified according to the microbiological finding as “most likely irrelevant” (no growth or contamination) or as “most likely pathogenic” (potentially pathogenic or pathogenic). The present study was part of a double-blind randomized placebo-controlled intervention study that analyzed the effect of a single dose of 80 mg of steroids on seroma formation after mastectomy

From: Bacterial colonization of seromas after breast cancer surgery with and without local steroid prophylaxis

 

Culture results

 

Bacterial classification

Treatment

Contaminant microorganism n (%)

Most likely pathogenic microorganism n (%)

Saline

254 (49.0%)

39 (7.5%)

Steroids

213 (5.1%)

95 (18.3%)*

Saline vs steroids odds ratio

(95% CI)

4.76

(3.10–7.31)

  1. *Significant more “probably pathogenic” growth occurred in the steroid group (Fisher’s exact test p < 0.001).