Table 2 Determination of predictive factors for 5-year overall survival by univariate analysis
Hazard ratio | 95% CI | p value | ||
|---|---|---|---|---|
Age | 1.068 | 1.045 | 1.093 | <0.001 |
Sex | ||||
Male | 1.000 | 0.474 | ||
Female | 0.833 | 0.504 | 1.375 | |
Tumor location | ||||
Lower | 1.000 | 0.181 | ||
Middle | 0.555 | 0.298 | 1.036 | |
Upper | 0.687 | 0.367 | 1.287 | |
Tumor size | ||||
< 60 mm | 1.000 | <0.001 | ||
≥ 60 mm | 6.029 | 3.707 | 9.806 | |
Tumor differentiation | ||||
Differentiation | 1.000 | 0.010 | ||
Undifferentiation | 1.869 | 1.163 | 3.002 | |
Laurenereclassification | ||||
Intestinal type | 1.000 | 0.026 | ||
Diffuse type | 1.837 | 1.154 | 2.924 | |
Mixed type | 0.000 | 0.000 | ||
T stage | ||||
1 | 1.000 | <0.001 | ||
2 | 1.552 | 0.528 | 4.562 | |
3 | 4.666 | 2.469 | 8.821 | |
4 | 14.343 | 8.057 | 25.530 | |
N stage | ||||
0 | 1.000 | <0.001 | ||
1 | 1.622 | 0.665 | 3.956 | |
2 | 2.740 | 1.235 | 6.080 | |
3 | 10.640 | 6.212 | 17.612 | |
TNM stage | ||||
I | 1.000 | <0.001 | ||
II | 2.660 | 1.303 | 5.429 | |
III | 11.783 | 6.751 | 20.567 | |
Lymphatic invasion | ||||
Negative | 1.000 | <0.001 | ||
Positive | 3.291 | 2.073 | 5.225 | |
Vascular invasion | ||||
Negative | 1.000 | 0.001 | ||
Positive | 2.541 | 1.436 | 4.496 | |
Perineural invasion | ||||
Negative | 1.000 | <0.001 | ||
Positive | 6.785 | 4.219 | 10.912 | |
HER 2 expression | ||||
0/1+ | 1.000 | 0.776 | ||
2+ | 0.880 | 0.526 | 1.473 | |
3+ | 0.844 | 0.499 | 1.427 | |