Table 3 Diagnostic potential of multifocal and bilateral tumors presence and tumors size above 5 mm as indicators of lymph node metastasis in PTMC patients
From: Which papillary thyroid microcarcinoma should be treated as “true cancer” and which as “precancer”?
ROC analysis | Presence of multifocal tumors | Presence of bilateral tumors | Presence of tumor ≥ 0.5 cm |
|---|---|---|---|
AUC (± 95%CI) | 0.747 (0.668–0.827) | 0.621 (0.529–0.713) | 0.827 (0.767–0.888) |
P value | < 0.0001 | < 0.0001 | < 0.0001 |
SE | 0.041 | 0.047 | 0.031 |
Sensitivity | 0.677 | 0.242 | 0.968 |
Specificity | 0.817 | 1.000 | 0.687 |
Accuracy | 0.768 | 0.734 | 0.785 |
LR (+) | 0.667 | 1.000 | 0.625 |
LR (−) | 0.825 | 0.710 | 0.975 |
PPV | 0.183 | 0.000 | 0.313 |
NPV | 0.323 | 0.758 | 0.032 |
Youden Index | 0.495 | 0.242 | 0.665 |