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Table 2 Entire cohort: univariate and multivariate analysis of factors influencing overall survival (n = 454)

From: Effect of clinical status on survival in patients with borderline or locally advanced pancreatic adenocarcinoma

 

Univariate

Multivariate

P

Hazard ratio

P

Underweight (BMI < 18.5 kg/m2)

.37

 

Performance status (0–1 versus 2–3)

< .01

1.6 (1.21–2.11)

< .01

Weight loss at diagnosis

< .01

 

Continuous weight loss at restaging

.01

9.56 (6.32–14.5)

< .01

Jaundice

.28

 

Pain

.12

 

CA 19-9 level

.08

 

Tumor location (head versus body/tail)

.54

 

Tumor staging (BRPC versus LAPC)

< .01

 

Resection

< .01

.38 (.284–.513)

< .01

  1. Entries in italic are significant, even if only in univariate analysis
  2. BMI body mass index, CA 19-9 carbohydrate antigene 19-9, BRPC borderline resectable pancreatic cancer, LAPC locally advanced pancreatic cancer