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Table 2 Entire cohort: univariate and multivariate analysis of factors influencing overall survival (n = 454)

From: Effect of clinical status on survival in patients with borderline or locally advanced pancreatic adenocarcinoma

  Univariate Multivariate
P Hazard ratio P
Underweight (BMI < 18.5 kg/m2) .37  
Performance status (0–1 versus 2–3) < .01 1.6 (1.21–2.11) < .01
Weight loss at diagnosis < .01  
Continuous weight loss at restaging .01 9.56 (6.32–14.5) < .01
Jaundice .28  
Pain .12  
CA 19-9 level .08  
Tumor location (head versus body/tail) .54  
Tumor staging (BRPC versus LAPC) < .01  
Resection < .01 .38 (.284–.513) < .01
  1. Entries in italic are significant, even if only in univariate analysis
  2. BMI body mass index, CA 19-9 carbohydrate antigene 19-9, BRPC borderline resectable pancreatic cancer, LAPC locally advanced pancreatic cancer