Table 3 Correlation of CD68+ TAMs at the tumour-infiltrating front (TIF) with clinicopathological characteristics in HCC
Variable | CD68+/TIF | CD68−/TIF | p value |
|---|---|---|---|
No. of patients | 53 | 5 | |
Patient age, years | 0.324 | ||
≤ 60 | 33 (62.3%) | 4 (80.0%) | |
> 60 | 20 (37.7%) | 1 (20.0%) | |
Gender | 0.430 | ||
Female | 42 (79.2%) | 3 (60.0%) | |
Male | 11 (20.8%) | 2 (40.0%) | |
Local tumour recurrence | 0.583 | ||
Positive | 15 (28.3%) | 2 (40.0%) | |
Negative | 38 (71.7%) | 3 (60.0%) | |
Overall tumour recurrence | 0.050 | ||
Positive | 19 (35.8%) | 4 (80.0%) | |
Negative | 34 (64.2%) | 1 (20.0%) | |
Distant Metastases | 0.209 | ||
Positive | 9 (17.0%) | 2 (40.0%) | |
Negative | 44 (83.0%) | 3 (60.0%) | |
Multiple tumour nodules | 0.035 | ||
Positive | 10 (18.9%) | 2 (40.0%) | |
Negative | 43 (81.1%) | 3 (60.0%) | |
Tumour size (mm) | 0.951 | ||
≤ 50 | 10 (10.0%) | 1 (20.0%) | |
> 50 | 43 (90.0%) | 4 (80.0%) | |
R status | 0.772 | ||
Positive | 8 (15.1%) | 1 (20.0%) | |
Negative | 45 (84.9%) | 4 (80.0%) | |
Angioinvasion | 0.583 | ||
Positive | 25 (47.2%) | 2 (40.0%) | |
Negative | 28 (52.8%) | 3 (60.0%) | |
Lymphangiosis carcinomatosa | 0.583 | ||
Positive | 15 (28.3%) | 2 (40.0%) | |
Negative | 38 (71.8%) | 3 (60.0%) | |
Histologic differentiation | 0.951 | ||
Well | 10 (10.0%) | 1 (20.0%) | |
Moderate/poor | 43 (90.0%) | 4 (80.0%) | |
Pathologic T stage | 0.148 | ||
T1/T2 | 28 (53.8%) | 1 (20.0%) | |
T3/T4 | 24 (46.2%) | 4 (80.0%) | |
Pathologic N stage | 0.658 | ||
Positive | 2 (03.8%) | 0 (00.0%) | |
Negative | 51 (96.2%) | 5 (100.0%) |