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Table 3 Correlation of CD68+ TAMs at the tumour-infiltrating front (TIF) with clinicopathological characteristics in HCC

From: Immunologic cellular characteristics of the tumour microenvironment of hepatocellular carcinoma drive patient outcomes

Variable CD68+/TIF CD68/TIF p value
No. of patients 53 5  
Patient age, years    0.324
 ≤ 60 33 (62.3%) 4 (80.0%)  
 > 60 20 (37.7%) 1 (20.0%)  
Gender    0.430
 Female 42 (79.2%) 3 (60.0%)  
 Male 11 (20.8%) 2 (40.0%)  
Local tumour recurrence    0.583
 Positive 15 (28.3%) 2 (40.0%)  
 Negative 38 (71.7%) 3 (60.0%)  
Overall tumour recurrence    0.050
 Positive 19 (35.8%) 4 (80.0%)  
 Negative 34 (64.2%) 1 (20.0%)  
Distant Metastases    0.209
 Positive 9 (17.0%) 2 (40.0%)  
 Negative 44 (83.0%) 3 (60.0%)  
Multiple tumour nodules    0.035
 Positive 10 (18.9%) 2 (40.0%)  
 Negative 43 (81.1%) 3 (60.0%)  
Tumour size (mm)    0.951
 ≤ 50 10 (10.0%) 1 (20.0%)  
 > 50 43 (90.0%) 4 (80.0%)  
R status    0.772
 Positive 8 (15.1%) 1 (20.0%)  
 Negative 45 (84.9%) 4 (80.0%)  
Angioinvasion    0.583
 Positive 25 (47.2%) 2 (40.0%)  
 Negative 28 (52.8%) 3 (60.0%)  
Lymphangiosis carcinomatosa    0.583
 Positive 15 (28.3%) 2 (40.0%)  
 Negative 38 (71.8%) 3 (60.0%)  
Histologic differentiation    0.951
 Well 10 (10.0%)   1 (20.0%)
 Moderate/poor 43 (90.0%)   4 (80.0%)
Pathologic T stage    0.148
 T1/T2 28 (53.8%) 1 (20.0%)  
 T3/T4 24 (46.2%) 4 (80.0%)  
Pathologic N stage    0.658
 Positive 2 (03.8%) 0 (00.0%)  
 Negative 51 (96.2%) 5 (100.0%)