Table 6 Summary of sensitivity analyses
Main analysis [RR (95% CI); P value; studies (N); I2] | Fixed effects [RR (95% CI); P value; studies (N); I2] | Exclusion of poor quality studies [RR (95% CI); P value; studies (N); I2] | Exclusion of studies with imputed data [RR (95% CI); P value; studies (N); I2] | |
|---|---|---|---|---|
LTR | 2.49 (1.19, 5.22); P = 0.016; 8; 84% | 1.56 (1.28, 1.90); P < 0.001; 8; 84% | 2.01 (1.06, 3.84); P = 0.033; 7; 72% | NA |
OS (1-year) | 1.01 (0.99, 1.03); P = 0.409; 10; 0% | 1.00 (0.97, 1.03); P = 0.977; 10; 0% | 1.00 (0.97, 1.03); P = 0.992; 9; 0% | NA |
OS (3-year) | 0.94 (0.88, 0.99); P = 0.03; 10; 0% | 0.92 (0.86, 0.99); P = 0.016; 10; 0% | 0.94 (0.88, 1.00); P = 0.061; 9; 0% | NA |
OS (5-year) | 0.88 (0.80, 0.97); P = 0.01; 9; 0% | 0.87 (0.79, 0.96); P = 0.008; 9; 0% | 0.88 (0.79, 0.98); P = 0.025; 8; 0% | NA |
IDL | 1.13 (0.80, 1.60); P = 0.474; 5; 75% | 1.12 (0.95, 1.33); P = 0.17; 5; 75% | 1.14 (0.74, 1.76); P = 0.544; 4; 81% | NA |
EHM | 1.10 (0.71, 1.72); P = 0.659; 2; 0% | 1.09 (0.70, 1.69); P = 0.71; 2; 0% | Too few studies (< 2) to inform | NA |
Operative time (min)* | − 58.69 (− 89.55, − 27.83); P < 0.001; 3; 94% | − 67.99 (− 74.36, − 61.61); P < 0.001; 3; 94% | − 44.61 (− 63.74, − 25.49); P < 0.001; 2; 49% | − 58.89 (− 100.15, − 17.63); P = 0.005; 2; 97% |
IBL (mL)* | − 189.09 (− 324.54, − 53.64); P = 0.006; 3; 93% | − 119.88 (− 146.57, − 91.19); P < 0.001; 3; 93% | − 189.09 (− 324.54, − 53.64); P = 0.006; 3; 93% | − 229.28 (− 512.69, 54.12); P = 0.113; 2; 97% |
LOS (days)* | − 6.16 (− 8.25, − 4.07); P < 0.001; 6; 84% | − 7.13 (− 7.78, − 6.48); P < 0.001; 6; 84% | − 6.14 (− 8.60, − 3.68); P < 0.001; 5; 87% | − 6.5 (− 9.52, − 3.48); P < 0.001; 4; 88% |
DFS (1-year) | 0.95 (0.90, 1.01); P = 0.085; 8; 39% | 0.94 (0.89, 0.99); P = 0.016; 8; 39% | 0.95 (0.90, 1.01); P = 0.085; 8; 39% | NA |
DFS (3-year) | 0.78 (0.65, 0.94); P = 0.009; 8; 59% | 0.76 (0.68, 0.85); P < 0.001; 8; 59% | 0.78 (0.65, 0.94); P = 0.009; 8; 59% | NA |
DFS (5-year) | 0.83 (0.58, 1.17); P = 0.284; 8; 71% | 0.79 (0.66, 0.95); P = 0.011; 8; 71% | 0.83 (0.58, 1.17); P = 0.284; 8; 71% | NA |
Overall complications | 0.31 (0.19, 0.51); P < 0.001; 9; 10% | 0.33 (0.21, 0.50); P < 0.001; 9; 10% | 0.32 (0.19,0.55); P < 0.001; 8; 19% | NA |
Major complications | 0.24 (0.10, 0.61); P = 0.002; 4; 0% | 0.23 (0.09, 0.59); P = 0.002; 4; 0% | Too few studies (< 2) to inform | NA |
Minor complications | 0.45 (0.23, 0.90); P = 0.024; 3; 66% | 0.43 (0.32, 0.59); P < 0.001; 3; 66% | 1.32 (0.04, 39.86); P = 0.872; 2; 83% | NA |