Skip to main content

Table 3 Summary of analyses: MWA + HR versus HR

From: Microwave ablation compared with hepatic resection for the treatment of hepatocellular carcinoma and liver metastases: a systematic review and meta-analysis

Outcome Number of studies included in meta-analysis* Summary effect† (95% CI); P value Heterogeneity (I2 value) (%)
Primary outcome
 LTR 3 0.63 (0.28, 1.41); P = 0.263 69
Secondary outcomes
 OS (1-year) 4 0.99 (0.88, 1.11); P = 0.867 48
 OS (3-year) 4 0.84 (0.49, 1.46); P = 0.541 82
 OS (5-year) 2 0.74 (0.19, 2.79); P = 0.651 91
 IDL 2 1.08 (0.61, 1.9); P = 0.793 51
 EHM† 2 0.82 (0.49, 1.39); P = 0.464 27
 Operative time (min) 4 13.93 ( 9.69, 37.54); P = 0.248 81
 Intraoperative blood loss (mL) 4 − 161.89 (− 291.49, − 32.30); P = 0.014 92
 Hospital length of stay (days) 2 0.08 ( 2.04, 2.19); P = 0.942 0
 DFS (1-year) 3 0.95 (0.65, 1.40); P = 0.80 82
 DFS (3-year) 3 1.01 (0.69, 1.48); P = 0.944 51
 Overall complications 5 0.86 (0.63, 1.18); P = 0.353 0
 Major complications 4 0.89 (0.57, 1.38); P = 0.588 12
 Minor complications 3 0.83 (0.64, 1.08); P = 0.174 0
 Blood transfusion 3 0.45 (0.14, 1.41); P = 0.171 85
  1. *Three studies [11, 12, 16] included in this comparison used microwave radiation for pre-transection coagulation rather than tumor ablation
  2. †Risk ratio (RR) for MWA + HR versus HR for all outcomes except operative time, intraoperative blood loss, and hospital length of stay, which are reported as the weighted mean difference (WMD). Italicized values indicate statistical significance. Point estimates and confidence intervals were calculated using a random effects model
  3. Abbreviations: CI confidence interval, DFS disease-free survival, EHM extrahepatic metastasis, IDL intrahepatic de novo lesions, HR hepatic resection, LTR local tumor recurrence, MWA microwave ablation, OS overall survival, RR risk ratio