Table 1 Study and baseline characteristics for studies included in the meta-analysis
First author | Year | Study design | Region | Population | Arm 1 | Arm 2 | Arm 3 | MWA approach | Patients (N) | Age (years) | Male (%) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MWA | HR | MWA + HR | |||||||||||
Xu, J [23] | 2015 | RCT | China | HCC | MWA | HR | – | Percutaneous | 45 | 45 | – | 58.1 | 73 |
Tanaka, K [4] | 2006 | Retrospective cohort | Japan | Metastases | – | HR | MWA + HR | – | – | 37 | 16 | 60.3 | 62 |
Wang, ZL [24] | 2008 | Retrospective cohort | China | HCC | MWA | HR | – | Percutaneous | 114 | 80 | – | 56.0 | 88 |
Imura, S [11] | 2012 | Prospective cohort | Japan | HCC | – | HR | MWA + HR | – | – | 10 | 12 | 65.6 | 68 |
Stattner, S [3] | 2013 | Retrospective cohort | UK | Metastases | MWA | – | MWA + HR | Open | 15 | – | 28 | 66.1 | 74 |
Takami, Y [25] | 2013 | Prospective cohort | Japan | HCC | MWA | HR | – | Thoracotomy, laparoscopy, or laparotomy | 390 | 34 | – | 67.5 | 62 |
Shi, J [26] | 2014 | Retrospective cohort | China | HCC | MWA | HR | – | NR | 117 | 107 | – | 55.6 | 80 |
Tan, K [12] | 2014 | Retrospective cohort | China | Metastases/ HCC* | – | HR | MWA + HR | – | – | 62 | 66 | 50.3 | 84 |
Zhang, EL [6] | 2016 | Retrospective cohort | China | HCC | MWA | HR | – | Percutaneous | 68 | 122 | – | 51.6 | 88 |
Li, W [27] | 2017 | Retrospective cohort | China | HCC | MWA | HR | – | Percutaneous, laparoscopic, and open | 60 | 220 | – | 62.5 | 82 |
Philips, P [13] | 2017 | Retrospective cohort | USA | Metastases/ HCC* | MWA | HR | MWA + HR | Laparoscopic and open | 108 | 84 | 84 | 61.0 | 55 |
Ryu, T [7] | 2017 | Retrospective cohort | Japan | Metastases | MWA | HR | MWA + HR | Open | 13 | 14 | 7 | 66.0 | 71 |
Song, P [14] | 2017 | Retrospective cohort | China | Metastases | MWA | HR | – | Percutaneous† | 28 | 34 | – | 60.0 | 53 |
Zhang, QB [15] | 2017 | Retrospective cohort | China | HCC | MWA | HR | – | Percutaneous | 31 | 42 | – | 53.2 | 67 |
Chen, ZB [16] | 2018 | Retrospective cohort | China | HCC | – | HR | MWA + HR | – | – | 191 | 112 | 51.6 | 73 |
Chong, CCN [17] | 2018 | Retrospective cohort | China | HCC | MWA | HR | – | Percutaneous, laparoscopic, and open | 63 | 63 | – | 63.8 | 71 |