Table 4 Tumor, patient, and treatment-related characteristics of patients undergoing neoadjuvant treatment without surgery per histology. AC adenocarcinoma, SCC squamous cell carcinoma, IQR interquartile range, nCRT neoadjuvant chemoradiotherapy, nCT neoadjuvant chemotherapy

Patients

n (%)

52 (45.6)

62 (54.4)

114

Gender

p = 0.093

 Male

n (%)

44 (84.6)

45 (72.6)

89

 Female

n (%)

8 (15.4)

17 (27.4)

25

Age

Median (IQR)

Mean (range)

67 (62–74)

67 (35–86)

64 (59–72)

64 (32–84)

67 (60–74)

65 (32–86)

p = 0.178

Time frame

p = 0.077

 Before 2011

n (%)

24 (46.2)

38 (61.3)

62

 From 2011

n (%)

28 (53.8)

24 (38.7)

52

Clinical stage

 cT1–2

n (%)

2 (3.8)

5 (8.1)

7

 cT3

n (%)

47 (90.4)

40 (64.5)

87

 cT3–4

n (%)

2 (3.8)

12 (19.4)

14

 cT4

n (%)

1 (1.9)

5 (8.1)

6

cN status

 cN positive

n (%)

48 (92.3)

55 (88.7)

103

 cN negative

n (%)

4 (7.7)

7 (11.3)

11

Treatment type

 nCRT

n (%)

37 (71.2)

56 (90.3)

93

 nCT

n (%)

15 (28.8)

6 (9.7)

21