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Table 4 Tumor, patient, and treatment-related characteristics of patients undergoing neoadjuvant treatment without surgery per histology. AC adenocarcinoma, SCC squamous cell carcinoma, IQR interquartile range, nCRT neoadjuvant chemoradiotherapy, nCT neoadjuvant chemotherapy

From: Analysis of patients scheduled for neoadjuvant therapy followed by surgery for esophageal cancer, who never made it to esophagectomy

   AC SCC ALL  
Patients n (%) 52 (45.6) 62 (54.4) 114  
Gender      p = 0.093
 Male n (%) 44 (84.6) 45 (72.6) 89
 Female n (%) 8 (15.4) 17 (27.4) 25
Age Median (IQR) Mean (range) 67 (62–74) 67 (35–86) 64 (59–72) 64 (32–84) 67 (60–74) 65 (32–86) p = 0.178
Time frame      p = 0.077
 Before 2011 n (%) 24 (46.2) 38 (61.3) 62
 From 2011 n (%) 28 (53.8) 24 (38.7) 52
Clinical stage      p = 0.009
 cT1–2 n (%) 2 (3.8) 5 (8.1) 7
 cT3 n (%) 47 (90.4) 40 (64.5) 87
 cT3–4 n (%) 2 (3.8) 12 (19.4) 14
 cT4 n (%) 1 (1.9) 5 (8.1) 6
cN status      p = 0.752
 cN positive n (%) 48 (92.3) 55 (88.7) 103
 cN negative n (%) 4 (7.7) 7 (11.3) 11
Treatment type      p = 0.008
 nCRT n (%) 37 (71.2) 56 (90.3) 93
 nCT n (%) 15 (28.8) 6 (9.7) 21