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Table 3 Tumor, patient, and treatment-related characteristics of patients undergoing neoadjuvant treatment without surgery per time cohort. IQR interquartile range, AC adenocarcinoma, SCC squamous cell carcinoma, nCRT neoadjuvant chemoradiotherapy, nCT neoadjuvant chemotherapy

From: Analysis of patients scheduled for neoadjuvant therapy followed by surgery for esophageal cancer, who never made it to esophagectomy

   Before 2011 From 2011 All  
Patients n (%) 62 (54.4) 52 (45.6) 114  
Gender      p = 0.342
 Male n (%) 47 (75.8) 42 (80.8) 89
 Female n (%) 15 (24.2) 10 (19.2) 25
Age Median (IQR) Mean (range) 65 (58–74) 64 (35–84) 68 (61–74) 67 (32–86) 67 (60–74) 65 (32–86) p = 0.224
Histology      p = 0.077
 AC n (%) 24 (38.7) 28 (53.8) 52
 SCC n (%) 38 (61.3) 24 (46.2) 62
Clinical stage      p = 0.131
 cT2 n (%) 4 (6.5) 3 (5.8) 7
 cT3 n (%) 45 (72.6) 42 (80.8) 87
 cT3–4 n (%) 7 (11.3) 7 (13.5) 14
 cT4 n (%) 6 (9.7) 0 (0.0) 6
cN status      p = 0.173
 cN negative n (%) 4 (6.5) 7 (13.5) 11
 cN positive n (%) 58 (93.5) 45 (86.5) 103
Treatment type      p = 0.513
 nCRT n (%) 51 (82.3) 42 (80.8) 93
 nCT n (%) 11 (17.7) 10 (19.2) 21