Fig. 3

In colon cancer, forest plots of the random-effect subgroup meta-analysis for the efficacy of CD8+ T cell for DFS (a) and OS (b), stratified analysis based on the location of lymphocyte infiltration, including invasive tumor margin (IM), tumor center (TC), tumor stroma (ST). The horizontal bars indicate the 95% CIs. ST+TC: analysis of infiltration density of tumor infiltrating lymphocytes based on tumor stroma and tumor center; TC+IM: analysis of infiltration density of tumor infiltrating lymphocytes based on tumor stroma and invasive tumor margin; LC: left sided colon; RC: right sided colon