|
Covariates
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
Hazard ratio (HR)
|
95% CI for HR
|
p value
|
Hazard ratio
|
95% CI for HR
|
p value
|
|---|
|
Age
|
1.02
|
0.98–1.05
|
0.28
|
1.02
|
0.98–1.05
|
0.35
|
|
Grade
|
|
Grade 3 vs. grades 1–2
|
2.48
|
1.25–4.92
|
0.01*
|
2.10
|
1.03–4.32
|
0.04*
|
|
Outer 1/3 invasion vs. inner 2/3
|
0.94
|
0.33–2.65
|
0.90
|
0.65
|
0.22–1.90
|
0.43
|
|
LVSI
|
2.12
|
1.05–4.28
|
0.04*
|
1.85
|
0.87–3.94
|
0.11
|
|
High-intermediate risk
|
1.74
|
0.91–3.32
|
0.92
|
–
|
–
|
–
|
- LVSI lymphovascular space invasion; *Significantly associated with shorter progression free survival
