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Table 4 Univariate and multivariate analysis for disease free survival

From: Peritoneal carcinomatosis index predicts survival in colorectal patients undergoing HIPEC using oxaliplatin: a retrospective single-arm cohort study

Covariates

Univariate analysis

Multivariate analysis

 

HR

95% CI

p value

HR

95% CI

p value

Age

1.026

(0.995–1.059)

0.096

   

Female

Ref

     

Male

1.4503

(0.8437–2.493)

0.179

   

Colon primary

Ref

     

Rectal primary

0.7183

(0.2847–1.812)

0.484

   

Classic adenocarcinoma

Ref

     

Mucinous adenocarcinoma

1.1205

(0.5979–2.1)

0.723

   

Grade I (histology)

Ref

     

Grade II (histology)

0.90843

(0.4726–1.746)

0.773

   

Grade III (histology)

0.73676

(0.3409–1.592)

0.437

   

Presenting stage I–III

Ref

     

Presenting stage IV

1.4028

(0.8112–2.426)

0.226

   

Metachronous

Ref

     

Synchronous

1.2770

(0.7426–2.196)

0.377

   

Peri-op chemo

0.419

(0.1873–0.938)

0.034

0.448

(0.1968–1.022)

0.056

Intra-op IV chemo

1.7762

(0.9555–3.302)

0.069

   

PCI (continuous)

1.101

(1.059–1.145)

1.09e−06

1.100

(1.047–1.156)

0.0001

Operative time (hours)

1.199

(1.068–1.346)

0.002

1.014

(0.875–1.175)

0.856

Blood loss (100 ml)

1.0177

(0.9875–1.047)

0.265

   

No complications

Ref

     

Grade I (complication)

1.072

(0.510–1.996)

0.838

   

Grade II (complication)

1.105

(0.472–2.576)

0.817

   

Grade III (complication)

1.936

(0.739–5.208)

0.185

   

Grade IV (complication)

1.849

(0.616–1.795)

0.260

   
  1. Boldface font indicate statistically significant p values of less than 0.05