Variable | Hazard ratio (95% CI) | p value |
---|---|---|
a. Tumour side left/right | ||
Male | 1 | |
Female | 0.819 (0.771–0.869) | < 0.0001 |
ASA I compared to ASA II | 0.728 (0.658–0.806) | < 0.0001* |
ASA II compared to ASA III | 0.613 (0.573–0.655) | < 0.0001* |
ASA III compared to ASA IV | 0.646 (0.552–0.756) | < 0.0001* |
Laparoscopic surgery | 1 | |
Open surgery | 1.127 (1.033–1.230) | 0.007 |
No blood transfusion | 1 | |
Blood transfusion | 1.315 (1.232–1.403) | < 0.0001 |
Age 65 years compared to 65–75 years | 0.693 (0.615–0.781) | < 0.0001* |
Age 65 years compared to age > 75 years | 0.504 (0.472–0.537) | < 0.0001* |
Year of diagnosis | 0.967 (0.952–0.983) | < 0.0001* |
LNY 0–5 compared to LNY 5–11 | 1.135 (1.019–1.264) | 0.021* |
LNY 5–11 compared to LNY 12–17 | 1.240 (1.148–1.340) | < 0.0001* |
LNY 12–17 compared to LNY ≥ 18 | 1.139 (1.054–1.230) | < 0.001* |
N0 | 1 | |
N1 + 2 | 0.609 (0.558–0.665) | < 0.0001 |
pT1 compared to pT2 | 0.817 (0.673–0.992) | 0.041* |
pT2 compared to pT3 | 0.824 (0.739–0.917) | < 0.0001* |
pT3 compared to pT4 | 0.614 (0.571–0.661) | < 0.0001* |
Tumour side left | 1 | |
Tumour side right | 1.069 (1.005–1.136) | 0.033 |
Charlson score 0 compared to score 1 | 0.792 (0.725–0.864) | < 0.0001 |
Charlson score 1 compared to score 2 | 0.908 (0.793–1.040) | 0.165 |
Charlson score 2 compared to score 3 | 0.835 (0.735–0.948) | 0.005 |
No leak | 1 | |
Leak | 1.759 (1.575–1.965) | < 0.0001 |
Elective surgery | 1 | |
Acute surgery | 1.756 (1.628–1.893) | < 0.0001 |
b. Tumour subsite | ||
Male | 1 | |
Female | 0.820 (0.772–0.870) | < 0.0001 |
ASA I compared to ASA II | 0.729 (0.659–0.806) | < 0.0001* |
ASA II compared to ASA III | 0.613 (0.573–0.656) | < 0.0001* |
ASA III compared to ASA IV | 0.646 (0.552–0.756) | < 0.0001* |
Laparoscopic surgery | 1 | |
Open surgery | 1.120 (1.026–1.233) | 0.007 |
No blood transfusion | 1 | |
Blood transfusion | 1.309 (1.226–1.397) | < 0.0001 |
Age 65 years compared to age 65–75 years | 0.691 (0.614–0.779) | < 0.0001* |
Age 65 years compared to age > 75 years | 0.503 (0.471–0.536) | < 0.0001* |
Year of diagnosis | 0.967 (0.951–0.982) | < 0.0001* |
LNY 0–5 compared to LNY 5–11 | 1.134 (1.018–1.262) | 0.023* |
LNY 5–11 compared to LNY 12–17 | 1.240 (1.147–1.339) | < 0.0001* |
LNY 12–17 compared to LNY ≥ 18 | 1.142 (1.057–1.234) | < 0.001* |
N0 | 1 | |
N1 + 2 | 0.606 (0.555–0.663) | < 0.0001 |
pT1 compared to pT2 | 0.818 (0.674–0.993) | 0.042* |
pT2 compared to pT3 | 0.825 (0.740–0.919) | < 0.0001* |
pT3 compared to pT4 | 0.614 (0.571–0.660) | < 0.0001* |
Sigmoid colon | 1 | |
Coecum | 1.077 (0.993–1.168) | 0.074 |
Ascending colon | 1.032 (0.937–1.137) | 0.519 |
Hepatic flexure | 1.213 (1.084–1.358) | < 0.001 |
Transverse colon | 1.058 (0.948–1.180) | 0.315 |
Splenic flexure | 1.181 (1.026–1.359) | 0.021 |
Descending colon | 0.945 (0.813–1.109) | 0.514 |
Charlson score 0 compared to score 1 | 0.792 (0.725–0.864) | < 0.0001* |
Charlson score 1 compared to score 2 | 0.908 (0.793–1.040) | 0.165* |
Charlson score 2 compared to score 3 | 0.835 (0.735–0.948) | 0.005* |
No leak | 1 | |
Leak | 1.753 (1.569–1.960) | < 0.0001 |
Elective surgery | 1 | |
Acute surgery | 1.753 (1.626–1.891) | < 0.0001 |