Table 3 PICOS criteria for inclusion and exclusion of studies
Parameter | Inclusion criteria | Exclusion criteria |
|---|---|---|
Patients | • Adults ≥ 18 years undergoing gastrectomy with D2 lymphadenectomy for locally advanced gastric adenocarcinoma | • Patients under 18 years of age • Patients undergoing gastrectomy for reasons other than gastric adenocarcinoma |
Intervention | • Laparoscopic or laparoscopically assisted surgery | • Hand-assisted surgery • Robotic surgery |
Comparator | • Open surgery |  |
Outcomes | • Studies including at least one of the following primary outcome measures: - Short-term mortality - Rate of anastomotic leakages - Postoperative serious adverse events within 30 days after surgery - Length of hospital stay - Health-related quality of life within three and 12 months after surgery | • Studies not including at least one of the primary outcome measures |
Study design | • Randomized controlled trials • At least 30 days of follow-up | • Trials that are not randomized controlled trials • Shorter follow-up than 30 days |