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Table 2 Summary of findings

From: Laparoscopic versus open gastrectomy for locally advanced gastric cancer: a systematic review and meta-analysis of randomized controlled studies

Outcomes Anticipated absolute effects (95% CI) Relative effect (95% CI) No. of participants (studies) Certainty of the evidence (Grade)
Risk with open gastrectomy Risk with laparoscopic gastrectomy
Postoperative serious adverse events 27 per 1000 27 per 1.000
(14 to 55)
RR 1.0100
(0.5027 to 2.0471)
1999
(4 RCTs)

Lowa
Anastomotic leakage 8 per 1000 15 per 1.000
(4 to 59)
RR 1.83
(0.47 to 7.04)
1899
(4 RCTs)

Very lowa, b, c
Length of hospital stay The mean length of hospital stay was 10.14 days The mean length of hospital stay in the intervention group was 0.81 days fewer (2.58 fewer to 0.96 more) (5 RCTs)
Lowa,d
Incision-to-closure time The mean incision-to-closure time was 19411 min The mean incision-to-closure time in the intervention group was 49.1 min higher (17.29 higher to 80.91 higher) (5 RCTs)
Moderated
Intraoperative blood loss The mean intraoperative blood loss was 145.26 ml The mean intraoperative blood loss in the intervention group was 42.38 ml fewer (98.73 fewer to 13.98 more) (4 RCTs)
Lowa, d
Harvested lymph nodes The mean harvested lymph nodes was 34.64 The mean harvested lymph nodes in the intervention group was 0.73 fewer (1.89 fewer to 0.43 more) (5 RCTs)
High
  1. aWide confidence intervals
  2. bBias due to learning curve issues
  3. cSmall number of events
  4. dStrong evidence for statistical heterogeneity