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Table 1 Baseline characteristics of the study groups

From: Surgical resection of the primary tumor leads to prolonged survival in metastatic pancreatic neuroendocrine carcinoma

Variable

Group

Patient characteristics

Total n = 350

Resection of primary tumor n = 50

No resection of primary tumor n = 300

p

Sex

    

0.101

Female

145 (41.4%)

26 (52.0%)

119 (39.7%)

 

Male

205 (58.6%)

24 (48.0%)

181 (60.3%)

 

Race

    

0.726

White

278 (79.4%)

39 (78.0%)

239 (79.7%)

 

Black

40 (11.4%)

5 (10.0%)

35 (11.7%)

 

Other

32 (9.1%)

6 (12.0%)

26 (8.7%)

 

Age

    

0.001

< 65 years

191 (54.6%)

38 (76.0%)

153 (51.0%)

 

≥ 65 years

159 (45.4%)

12 (24.0%)

147 (49.0%)

 

Grade

    

0.284

III

236 (67.4%)

37 (74.0%)

199 (66.3%)

 

IV

114 (32.6%)

13 (26.0%)

101 (33.7%)

 

Tumor size

    

< 0.001*

< 2 cm

4 (1.1%)

1 (2.0%)

3 (1.0%)

0.872

2–4 cm

96 (27.4%)

20 (40.0%)

76 (25.3%)

 

> 4 cm

152 (43.4%)

28 (56.0%)

124 (41.3%)

 

Unknown

98 (28.0%)

1 (2.0%)

97 (32.3%)

 

Tumor location

    

< 0.001*

Head/overlapping

177 (50.6%)

23 (46.0%)

154 (51.3%)

0.016

Body/tail

108 (30.9%)

26 (52.0%)

82 (27.3%)

 

Unknown

65 (18.6%)

1 (2.0%)

64 (21.3%)

 

Lymph node metastases

    

< 0.001*

No

14 (4.0%)

8 (16.0%)

6 (2.0%)

0.078

Yes

46 (13.1%)

37 (74.0%)

9 (3.0%)

 

Unknown

290 (82.9%)

5 (10.0%)

285 (95.0%)

 

Chemotherapy

    

0.017

No

129 (36.9%)

26 (52.0%)

103 (34.3%)

 

Yes

221 (63.1%)

24 (48.0%)

197 (65.7%)

 

Year of diagnosis

    

0.099

< 2010

212 (60.6%)

25 (50%)

187 (62.3%)

 

≥ 2010

138 (39.4%)

25 (50%)

113 (37.7%)

 
  1. *p value among all groups. p value among the groups except the “unknown” group