Fig. 3

Histological features of intracranial and intestinal samples. a Resection of the right occipital lesion: pseudosarcomateous proliferation of atypical fusiform cells with focal progesterone receptors and EMA (not shown) expression consistent with a malignant meningioma, WHO grade III. b Resection of one of the new occipital lesion showing the same proliferation with focal expression of progesterone receptors. Melanoma’s markers, such as SOX10 or HMB45 and Melan A (not shown), were not expressed. c Intestinal resection showing a morphologically similar proliferation involving the mucosa and the sub-mucosa. Immunohistochemical phenotype was similar too with focal expression of progesterone receptors and negativity of melanocytic markers (SOX10, HMB45, and Melan A)